neo-Clerodane diterpenoids from the aerial parts of Teucrium fruticans cultivated in China.
Phytochemistry
; 119: 26-31, 2015 Nov.
Article
em En
| MEDLINE
| ID: mdl-26454794
ABSTRACT
Seven neo-clerodane diterpenes, teufruintins A-G (1-7), together with eight known compounds (8-15) were isolated from the CHCl3-soluble fraction of the aerial parts of Teucrium fruticans cultivated in China. The chemical structures of the isolated compounds were elucidated using different spectroscopic methods. All of the isolated diterpenes were evaluated for their cytotoxic activities on three human cancer cell lines, and for their ability to inhibit LPS-induced nitric oxide production in RAW 264.7 macrophages. None of the compounds displayed cytotoxic activities on the cancer cell lines, and only 15 showed weak NO inhibitory activity.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Medicamentos de Ervas Chinesas
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Teucrium
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Componentes Aéreos da Planta
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Diterpenos Clerodânicos
Limite:
Animals
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Humans
Idioma:
En
Revista:
Phytochemistry
Ano de publicação:
2015
Tipo de documento:
Article