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Excess TGF-ß mediates muscle weakness associated with bone metastases in mice.
Waning, David L; Mohammad, Khalid S; Reiken, Steven; Xie, Wenjun; Andersson, Daniel C; John, Sutha; Chiechi, Antonella; Wright, Laura E; Umanskaya, Alisa; Niewolna, Maria; Trivedi, Trupti; Charkhzarrin, Sahba; Khatiwada, Pooja; Wronska, Anetta; Haynes, Ashley; Benassi, Maria Serena; Witzmann, Frank A; Zhen, Gehua; Wang, Xiao; Cao, Xu; Roodman, G David; Marks, Andrew R; Guise, Theresa A.
Afiliação
  • Waning DL; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Mohammad KS; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Reiken S; Department of Physiology and Cellular Biophysics, Helen and Clyde Wu Center for Molecular Cardiology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Xie W; Department of Physiology and Cellular Biophysics, Helen and Clyde Wu Center for Molecular Cardiology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Andersson DC; Department of Physiology and Cellular Biophysics, Helen and Clyde Wu Center for Molecular Cardiology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • John S; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Chiechi A; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Wright LE; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Umanskaya A; Department of Physiology and Cellular Biophysics, Helen and Clyde Wu Center for Molecular Cardiology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Niewolna M; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Trivedi T; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Charkhzarrin S; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Khatiwada P; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Wronska A; Department of Physiology and Cellular Biophysics, Helen and Clyde Wu Center for Molecular Cardiology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Haynes A; Department of Physiology and Cellular Biophysics, Helen and Clyde Wu Center for Molecular Cardiology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
  • Benassi MS; Laboratory of Experimental Oncology, Instituto Ortopedico Rizzoli, Bologna, Italy.
  • Witzmann FA; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Zhen G; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Wang X; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Cao X; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Roodman GD; Department of Medicine, Division of Hematology/Oncology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Marks AR; Richard L. Roudebush VA Medical Center, Indianapolis, Indiana, USA.
  • Guise TA; Department of Physiology and Cellular Biophysics, Helen and Clyde Wu Center for Molecular Cardiology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Nat Med ; 21(11): 1262-1271, 2015 Nov.
Article em En | MEDLINE | ID: mdl-26457758

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteólise / Neoplasias Ósseas / Cálcio / Fator de Crescimento Transformador beta / Músculo Esquelético / Debilidade Muscular / Canal de Liberação de Cálcio do Receptor de Rianodina / Neoplasias Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteólise / Neoplasias Ósseas / Cálcio / Fator de Crescimento Transformador beta / Músculo Esquelético / Debilidade Muscular / Canal de Liberação de Cálcio do Receptor de Rianodina / Neoplasias Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos