A Cytosolic Multiprotein Complex Containing p85&#945; Is Required for ß-Catenin Activation in Colitis and Colitis-associated Cancer.

Goretsky, Tatiana; Bradford, Emily M; Ryu, Hyunji; Tahir, Maryam; Moyer, Mary Pat; Gao, Tianyan; Li, Linheng; Barrett, Terrence A

A Cytosolic Multiprotein Complex Containing p85α Is Required for ß-Catenin Activation in Colitis and Colitis-associated Cancer.

Goretsky, Tatiana; Bradford, Emily M; Ryu, Hyunji; Tahir, Maryam; Moyer, Mary Pat; Gao, Tianyan; Li, Linheng; Barrett, Terrence A.

Afiliação

Goretsky T; From the Department of Internal Medicine, Division of Gastroenterology, University of Kentucky, Lexington, Kentucky 40536.
Bradford EM; From the Department of Internal Medicine, Division of Gastroenterology, University of Kentucky, Lexington, Kentucky 40536.
Ryu H; the Washington University School of Medicine, St. Louis, Missouri 63110.
Tahir M; From the Department of Internal Medicine, Division of Gastroenterology, University of Kentucky, Lexington, Kentucky 40536.
Moyer MP; INCELL Corporation, San Antonio, Texas 78249.
Gao T; the Markey Cancer Center, University of Kentucky, Lexington, Kentucky 40536, and.
Li L; the Stowers Institute for Medical Research, Department of Pathology & Laboratory Medicine, The University of Kansas School of Medicine, Kansas City, Kansas 66160.
Barrett TA; From the Department of Internal Medicine, Division of Gastroenterology, University of Kentucky, Lexington, Kentucky 40536, t.barrett@uky.edu.

J Biol Chem ; 291(8): 4166-77, 2016 Feb 19.

Article em En | MEDLINE | ID: mdl-26565021

Assuntos

Classe Ia de Fosfatidilinositol 3-Quinase/metabolismo; Colite/metabolismo; Neoplasias do Colo/metabolismo; Complexos Multiproteicos/metabolismo; Proteínas de Neoplasias/metabolismo; Transdução de Sinais; beta Catenina/metabolismo; Animais; Classe Ia de Fosfatidilinositol 3-Quinase/genética; Colite/genética; Colite/patologia; Neoplasias do Colo/genética; Neoplasias do Colo/patologia; Humanos; Camundongos; Camundongos Transgênicos; Complexos Multiproteicos/genética; Proteínas de Neoplasias/genética; beta Catenina/genética

Palavras-chave

beta-catenin (B-catenin); colitis; colorectal cancer; phosphatidylinositide 3-kinase (PI 3-kinase); signal transduction; stem cells; ß-catenin

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Colite / Neoplasias do Colo / Complexos Multiproteicos / Beta Catenina / Classe Ia de Fosfatidilinositol 3-Quinase / Proteínas de Neoplasias Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2016 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google