Grape Cells (Multinucleated Keratinocytes) in Noninfectious Dermatoses: Case Series and Review of the Literature.
Am J Dermatopathol
; 37(12): e143-6, 2015 Dec.
Article
em En
| MEDLINE
| ID: mdl-26588345
ABSTRACT
Multinucleated keratinocytes (also known as multinucleated epidermal giant cells) are a frequently overlooked histological finding in noninfectious inflammatory dermatoses. They are sometimes found in conditions characterized by chronic rubbing and pruritus, such as lichen simplex chronicus or prurigo nodularis, and may be a helpful clue in making the clinical diagnosis. This finding must be differentiated from other conditions characterized by multinucleated keratinocytes on histopathology, specifically herpes simplex, varicella zoster, or measles viral infections. The authors present a case series of 2 patients with unique clinical noninfectious diagnoses but similar histopathologic findings on biopsy. The histopathologic findings on both cases demonstrated multinucleated keratinocytes, which were related to manipulation of the epidermis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células Gigantes
/
Queratinócitos
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Neurodermatite
Limite:
Adolescent
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Adult
/
Female
/
Humans
Idioma:
En
Revista:
Am J Dermatopathol
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Moldávia