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Efficiency and safety of surgical intervention to patients with Non-Cystic Fibrosis bronchiectasis: a meta-analysis.
Fan, Li-Chao; Liang, Shuo; Lu, Hai-Wen; Fei, Ke; Xu, Jin-Fu.
Afiliação
  • Fan LC; Department of Respiratory Medicine, Shanghai pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
  • Liang S; Department of Respiratory Medicine, Shanghai pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
  • Lu HW; Department of Respiratory Medicine, Shanghai pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
  • Fei K; Department of Thoracic Surgery, Shanghai pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
  • Xu JF; Department of Respiratory Medicine, Shanghai pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Sci Rep ; 5: 17382, 2015 Dec 02.
Article em En | MEDLINE | ID: mdl-26627202
No quantitative systematic review was found to report the efficiency and safety of surgical resection in the management of non-cystic fibrosis (non-CF) bronchiectasis. We therefore conducted a meta-analysis to assess the effects of operative intervention to patients with non-CF bronchiectasis. PubMed, the Cochrane library and Web of Science databases were searched up to July 8th, 2015. The pooled mortality from 34 studies recruiting 4788 patients was 1.5% (95% CI, 0.9-2.5%). The pooled morbidity from 33 studies consisting of 4583 patients was 16.7% (95% CI, 14.8-18.6%). The pooled proportion of patients from 35 studies, consisting of 4614 patients who were free of symptoms was 66.5% (95% CI, 61.3-71.7%) after surgery. The summary proportion of patients from 35 articles including 4279 participants who were improved was 27.5% (95% CI, 22.5-32.5%), and 9.1% (95% CI, 7.3-11.5%) showed no clinical improvement. In conclusion, our analysis indicated that lung resection in the management of non-CF bronchiectasis is associated with significant improvements in symptoms, low risk of mortality and acceptable morbidity.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Procedimentos Cirúrgicos Operatórios / Bronquiectasia Tipo de estudo: Systematic_reviews Limite: Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Procedimentos Cirúrgicos Operatórios / Bronquiectasia Tipo de estudo: Systematic_reviews Limite: Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido