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PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype.
Duan, Shunlei; Yuan, Guohong; Liu, Xiaomeng; Ren, Ruotong; Li, Jingyi; Zhang, Weizhou; Wu, Jun; Xu, Xiuling; Fu, Lina; Li, Ying; Yang, Jiping; Zhang, Weiqi; Bai, Ruijun; Yi, Fei; Suzuki, Keiichiro; Gao, Hua; Esteban, Concepcion Rodriguez; Zhang, Chuanbao; Izpisua Belmonte, Juan Carlos; Chen, Zhiguo; Wang, Xiaomin; Jiang, Tao; Qu, Jing; Tang, Fuchou; Liu, Guang-Hui.
Afiliação
  • Duan S; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Yuan G; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Liu X; Biodynamic Optical Imaging Center, College of Life Sciences, Peking University, Beijing 100871, China.
  • Ren R; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Li J; FSU-CAS Innovation Institute, Foshan 528000, China.
  • Zhang W; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
  • Wu J; Biodynamic Optical Imaging Center, College of Life Sciences, Peking University, Beijing 100871, China.
  • Xu X; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA.
  • Fu L; Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.
  • Li Y; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Yang J; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Zhang W; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Bai R; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Yi F; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Suzuki K; FSU-CAS Innovation Institute, Foshan 528000, China.
  • Gao H; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
  • Esteban CR; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Zhang C; Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.
  • Izpisua Belmonte JC; Universidad Católica San Antonio de Murcia (UCAM) Campus de los Jerónimos, No 135 Guadalupe, 30107 Murcia, Spain.
  • Chen Z; Research Center for Translational Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
  • Wang X; Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.
  • Jiang T; Beijing Institute for Brain Disorders, Beijing 100069, China.
  • Qu J; Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.
  • Tang F; Cell Therapy Center, Xuanwu Hospital Capital Medical University, Beijing 100053, China.
  • Liu GH; Beijing Institute for Brain Disorders, Beijing 100069, China.
Nat Commun ; 6: 10068, 2015 Dec 03.
Article em En | MEDLINE | ID: mdl-26632666
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias Encefálicas / Glioblastoma / PTEN Fosfo-Hidrolase / Células-Tronco Neurais Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias Encefálicas / Glioblastoma / PTEN Fosfo-Hidrolase / Células-Tronco Neurais Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido