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Ibrutinib combined with bendamustine and rituximab compared with placebo, bendamustine, and rituximab for previously treated chronic lymphocytic leukaemia or small lymphocytic lymphoma (HELIOS): a randomised, double-blind, phase 3 study.
Chanan-Khan, Asher; Cramer, Paula; Demirkan, Fatih; Fraser, Graeme; Silva, Rodrigo Santucci; Grosicki, Sebastian; Pristupa, Aleksander; Janssens, Ann; Mayer, Jiri; Bartlett, Nancy L; Dilhuydy, Marie-Sarah; Pylypenko, Halyna; Loscertales, Javier; Avigdor, Abraham; Rule, Simon; Villa, Diego; Samoilova, Olga; Panagiotidis, Panagiots; Goy, Andre; Mato, Anthony; Pavlovsky, Miguel A; Karlsson, Claes; Mahler, Michelle; Salman, Mariya; Sun, Steven; Phelps, Charles; Balasubramanian, Sriram; Howes, Angela; Hallek, Michael.
Afiliação
  • Chanan-Khan A; Mayo Clinic Cancer Center, Jacksonville, FL, USA. Electronic address: Chanan-Khan.Asher@mayo.edu.
  • Cramer P; Department I of Internal Medicine and German CLL Study Group, University of Cologne, Cologne, Germany.
  • Demirkan F; Division of Hematology, Dokuz Eylul University, Izmir, Turkey.
  • Fraser G; Juravinski Cancer Centre, McMaster University, Hamilton, ON, Canada.
  • Silva RS; IEP São Lucas/Hemomed Oncologia e Hematologia, São Paulo, Brazil.
  • Grosicki S; Department of Cancer Prevention, Faculty of Public Health, Silesian Medical University, Katowice, Poland.
  • Pristupa A; Regional Clinical Hospital, Ryazan, Russia.
  • Janssens A; Universitaire Ziekenhuizen Leuven, Leuven, Belgium.
  • Mayer J; Department of Internal Medicine, Hematology and Oncology, Masaryk University Hospital Brno, Jihlavska, Brno, Czech Republic.
  • Bartlett NL; Washington University School of Medicine, Siteman Cancer Center, St Louis, MO, USA.
  • Dilhuydy MS; Hôpital Haut-Lévêque, Bordeaux, Pessac, France.
  • Pylypenko H; Department of Hematology, Cherkassy Regional Oncological Center, Cherkassy, Ukraine.
  • Loscertales J; Hematology Department, Hospital Universitario La Princesa, IIS-IP, Madrid, Spain.
  • Avigdor A; Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Tel-Hashomer and Sackler School of Medicine, University of Tel-Aviv, Tel-Aviv, Israel.
  • Rule S; Department of Haematology, Derriford Hospital, Plymouth, UK.
  • Villa D; Division of Medical Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada.
  • Samoilova O; Nizhny Novogorod Regional Clinical Hospital, Nizhny Novogorod, Russia.
  • Panagiotidis P; 1st Department of Propedeutic Medicine, University of Athens, Athens, Greece.
  • Goy A; John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ, USA.
  • Mato A; John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ, USA; Center for CLL, University of Pennsylvania, Philadelphia, PA, USA.
  • Pavlovsky MA; Department of Hematology, Fundaleu, Buenos Aires, Argentina.
  • Karlsson C; Department of Hematology, Karolinska University Hospital, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Mahler M; Janssen Research & Development, Raritan, NJ, USA.
  • Salman M; Janssen Research & Development, Raritan, NJ, USA.
  • Sun S; Janssen Research & Development, Raritan, NJ, USA.
  • Phelps C; Janssen Research & Development, Raritan, NJ, USA.
  • Balasubramanian S; Janssen Research & Development, Spring House, PA, USA.
  • Howes A; Janssen Research & Development, High Wycombe, UK.
  • Hallek M; Department I of Internal Medicine, Center of Integrated Oncology, University of Cologne and Cologne Cluster of Excellence in Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany.
Lancet Oncol ; 17(2): 200-211, 2016 Feb.
Article em En | MEDLINE | ID: mdl-26655421
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Protocolos de Quimioterapia Combinada Antineoplásica / Hemorragia Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Protocolos de Quimioterapia Combinada Antineoplásica / Hemorragia Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de publicação: Reino Unido