Novel cycloartane triterpenoid from Cimicifuga foetida (Sheng ma) induces mitochondrial apoptosis via inhibiting Raf/MEK/ERK pathway and Akt phosphorylation in human breast carcinoma MCF-7 cells.

Sun, Hai-Yan; Liu, Bei-Bei; Hu, Jian-Yang; Xu, Li-Jia; Chan, Shun-Wan; Chan, Chi-On; Mok, Daniel K W; Zhang, Dong-Mei; Ye, Wen-Cai; Chen, Si-Bao

Sun, Hai-Yan; Liu, Bei-Bei; Hu, Jian-Yang; Xu, Li-Jia; Chan, Shun-Wan; Chan, Chi-On; Mok, Daniel K W; Zhang, Dong-Mei; Ye, Wen-Cai; Chen, Si-Bao.

Afiliação

Sun HY; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China ; State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Hong Kong Polytechnic University, Hong Kong, China.
Liu BB; State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Hong Kong Polytechnic University, Hong Kong, China.
Hu JY; College of Pharmacy, Jinan University, Guangzhou, China.
Xu LJ; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chan SW; State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Hong Kong Polytechnic University, Hong Kong, China.
Chan CO; State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Hong Kong Polytechnic University, Hong Kong, China.
Mok DK; State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Hong Kong Polytechnic University, Hong Kong, China.
Zhang DM; College of Pharmacy, Jinan University, Guangzhou, China.
Ye WC; College of Pharmacy, Jinan University, Guangzhou, China.
Chen SB; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China ; State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Hong Kong Polytechnic University, Hong Kong, China.

Chin Med ; 11: 1, 2016.

Article em En | MEDLINE | ID: mdl-26759603

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Chin Med Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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