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A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response.
Koday, Merika Treants; Nelson, Jorgen; Chevalier, Aaron; Koday, Michael; Kalinoski, Hannah; Stewart, Lance; Carter, Lauren; Nieusma, Travis; Lee, Peter S; Ward, Andrew B; Wilson, Ian A; Dagley, Ashley; Smee, Donald F; Baker, David; Fuller, Deborah Heydenburg.
Afiliação
  • Koday MT; Department of Microbiology, University of Washington, Seattle, Washington, United States of America.
  • Nelson J; Institute for Protein Design, Department of Biochemistry, University of Washington, Seattle, Washington, United States of America.
  • Chevalier A; Institute for Protein Design, Department of Biochemistry, University of Washington, Seattle, Washington, United States of America.
  • Koday M; Washington National Primate Research Center, University of Washington, Seattle, Washington, United States of America.
  • Kalinoski H; Department of Microbiology, University of Washington, Seattle, Washington, United States of America.
  • Stewart L; Institute for Protein Design, Department of Biochemistry, University of Washington, Seattle, Washington, United States of America.
  • Carter L; Institute for Protein Design, Department of Biochemistry, University of Washington, Seattle, Washington, United States of America.
  • Nieusma T; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
  • Lee PS; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
  • Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
  • Wilson IA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
  • Dagley A; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America.
  • Smee DF; Institute for Antiviral Research, Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah, United States of America.
  • Baker D; Institute for Antiviral Research, Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah, United States of America.
  • Fuller DH; Institute for Protein Design, Department of Biochemistry, University of Washington, Seattle, Washington, United States of America.
PLoS Pathog ; 12(2): e1005409, 2016 Feb.
Article em En | MEDLINE | ID: mdl-26845438
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Proteínas de Transporte / Glicoproteínas de Hemaglutininação de Vírus da Influenza / Influenza Humana / Anticorpos Antivirais Limite: Animals / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Proteínas de Transporte / Glicoproteínas de Hemaglutininação de Vírus da Influenza / Influenza Humana / Anticorpos Antivirais Limite: Animals / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos