Extensive tumoral melanosis associated with ipilimumab-treated melanoma.
Br J Dermatol
; 175(2): 391-3, 2016 Aug.
Article
em En
| MEDLINE
| ID: mdl-26877232
ABSTRACT
Tumoral melanosis describes a pigmented lesion clinically similar to melanoma but on histology reveals dense aggregates of melanin-laden, benign macrophages without malignant cells. In the few reported cases so far, tumoral melanosis has arisen in the skin or lymph node of a patient with a regressed melanoma or an epithelioid tumour. As a marker of regressed primary melanoma, its discovery may prompt investigation and surveillance for undiagnosed local or metastatic disease. Here, we present a unique case of extensive tumoral melanosis arising during ipilimumab treatment of in-transit metastases from a previously excised melanoma.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Melanoma
/
Melanose
/
Anticorpos Monoclonais
/
Antineoplásicos
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Br J Dermatol
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Estados Unidos