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Increased susceptibility to metabolic dysregulation in a mouse model of Alzheimer's disease is associated with impaired hypothalamic insulin signaling and elevated BCAA levels.
Ruiz, Henry H; Chi, Tiffany; Shin, Andrew C; Lindtner, Claudia; Hsieh, Wilson; Ehrlich, Michelle; Gandy, Sam; Buettner, Christoph.
Afiliação
  • Ruiz HH; Department of Medicine, Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Chi T; Department of Medicine, Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Shin AC; Department of Medicine, Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Lindtner C; Department of Medicine, Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Hsieh W; Department of Medicine, Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Ehrlich M; Department of Neurology and Pediatrics, Mount Sinai School of Medicine, New York, NY, USA.
  • Gandy S; Department of Neurology, Alzheimer's Disease Research Center, Mount Sinai School of Medicine, New York, NY, USA; Department of Psychiatry, Alzheimer's Disease Research Center, Mount Sinai School of Medicine, New York, NY, USA.
  • Buettner C; Department of Medicine, Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: christoph.buettner@mssm.edu.
Alzheimers Dement ; 12(8): 851-61, 2016 08.
Article em En | MEDLINE | ID: mdl-26928090
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Doença de Alzheimer / Aminoácidos de Cadeia Ramificada / Hipotálamo / Insulina / Doenças Metabólicas Tipo de estudo: Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Alzheimers Dement Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Doença de Alzheimer / Aminoácidos de Cadeia Ramificada / Hipotálamo / Insulina / Doenças Metabólicas Tipo de estudo: Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Alzheimers Dement Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos