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NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.
Ma, Chi; Kesarwala, Aparna H; Eggert, Tobias; Medina-Echeverz, José; Kleiner, David E; Jin, Ping; Stroncek, David F; Terabe, Masaki; Kapoor, Veena; ElGindi, Mei; Han, Miaojun; Thornton, Angela M; Zhang, Haibo; Egger, Michèle; Luo, Ji; Felsher, Dean W; McVicar, Daniel W; Weber, Achim; Heikenwalder, Mathias; Greten, Tim F.
Afiliação
  • Ma C; Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Kesarwala AH; Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Eggert T; Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Medina-Echeverz J; Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Kleiner DE; Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Jin P; Cell Processing Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Stroncek DF; Cell Processing Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Terabe M; Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Kapoor V; Experimental Transplantation and Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • ElGindi M; Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Han M; Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Thornton AM; Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Zhang H; Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Egger M; Institute of Surgical Pathology, University and University Hospital Zurich, Zurich 8091, Switzerland.
  • Luo J; Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Felsher DW; Division of Oncology, Department of Medicine and Pathology, Stanford University, California 94305, USA.
  • McVicar DW; Cancer and Inflammation Program, National Cancer Institute, Frederick, Maryland 21702, USA.
  • Weber A; Institute of Surgical Pathology, University and University Hospital Zurich, Zurich 8091, Switzerland.
  • Heikenwalder M; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich 81675, Germany.
  • Greten TF; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany.
Nature ; 531(7593): 253-7, 2016 Mar 10.
Article em En | MEDLINE | ID: mdl-26934227
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Carcinoma Hepatocelular / Carcinogênese / Hepatopatia Gordurosa não Alcoólica / Neoplasias Hepáticas Tipo de estudo: Etiology_studies / Observational_studies Idioma: En Revista: Nature Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Carcinoma Hepatocelular / Carcinogênese / Hepatopatia Gordurosa não Alcoólica / Neoplasias Hepáticas Tipo de estudo: Etiology_studies / Observational_studies Idioma: En Revista: Nature Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido