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IL-2 consumption by highly activated CD8 T cells induces regulatory T-cell dysfunction in patients with hemophagocytic lymphohistiocytosis.
Humblet-Baron, Stéphanie; Franckaert, Dean; Dooley, James; Bornschein, Simon; Cauwe, Bénédicte; Schönefeldt, Susann; Bossuyt, Xavier; Matthys, Patrick; Baron, Frédéric; Wouters, Carine; Liston, Adrian.
Afiliação
  • Humblet-Baron S; Translational Immunology Laboratory, VIB, Leuven, Belgium; Department of Microbiology and Immunology, KUL-University of Leuven, Leuven, Belgium.
  • Franckaert D; Translational Immunology Laboratory, VIB, Leuven, Belgium; Department of Microbiology and Immunology, KUL-University of Leuven, Leuven, Belgium.
  • Dooley J; Translational Immunology Laboratory, VIB, Leuven, Belgium; Department of Microbiology and Immunology, KUL-University of Leuven, Leuven, Belgium.
  • Bornschein S; Translational Immunology Laboratory, VIB, Leuven, Belgium; Department of Microbiology and Immunology, KUL-University of Leuven, Leuven, Belgium.
  • Cauwe B; Translational Immunology Laboratory, VIB, Leuven, Belgium; Department of Microbiology and Immunology, KUL-University of Leuven, Leuven, Belgium.
  • Schönefeldt S; Translational Immunology Laboratory, VIB, Leuven, Belgium; Department of Microbiology and Immunology, KUL-University of Leuven, Leuven, Belgium.
  • Bossuyt X; Department of Microbiology and Immunology, KUL-University of Leuven, Leuven, Belgium; University Hospitals Leuven, Leuven, Belgium.
  • Matthys P; Rega Institute, KUL-University of Leuven, Leuven, Belgium.
  • Baron F; GIGA I(3) and the Department of Hematology, University of Liège, Liege, Belgium.
  • Wouters C; University Hospitals Leuven, Leuven, Belgium; Pediatric Immunology, KUL-University of Leuven, Leuven, Belgium.
  • Liston A; Translational Immunology Laboratory, VIB, Leuven, Belgium; Department of Microbiology and Immunology, KUL-University of Leuven, Leuven, Belgium. Electronic address: adrian.liston@vib.be.
J Allergy Clin Immunol ; 138(1): 200-209.e8, 2016 07.
Article em En | MEDLINE | ID: mdl-26947179
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-2 / Linfócitos T Reguladores / Linfócitos T CD8-Positivos / Linfo-Histiocitose Hemofagocítica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Bélgica País de publicação: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-2 / Linfócitos T Reguladores / Linfócitos T CD8-Positivos / Linfo-Histiocitose Hemofagocítica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Bélgica País de publicação: Estados Unidos