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Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs.
Plath, Friederike; Ringler, Philippe; Graff-Meyer, Alexandra; Stahlberg, Henning; Lauer, Matthias E; Rufer, Arne C; Graewert, Melissa A; Svergun, Dmitri; Gellermann, Gerald; Finkler, Christof; Stracke, Jan O; Koulov, Atanas; Schnaible, Volker.
Afiliação
  • Plath F; a Analytical Development and Quality Control, Pharmaceutical Technical Development Europe, F. Hoffmann-La Roche Ltd. , Basel , Switzerland.
  • Ringler P; b Center for Cellular Imaging and Nano Analytics, Biozentrum University of Basel , Basel , Switzerland.
  • Graff-Meyer A; c Friedrich Miescher Institute for Biomedical Research , Basel , Switzerland.
  • Stahlberg H; b Center for Cellular Imaging and Nano Analytics, Biozentrum University of Basel , Basel , Switzerland.
  • Lauer ME; d Chemical Biology, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , Basel , Switzerland.
  • Rufer AC; d Chemical Biology, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , Basel , Switzerland.
  • Graewert MA; e European Molecular Biology Laboratory, Hamburg Outstation , Hamburg , Germany.
  • Svergun D; e European Molecular Biology Laboratory, Hamburg Outstation , Hamburg , Germany.
  • Gellermann G; f Novartis Pharma AG, Werk Klybeck , Basel , Switzerland.
  • Finkler C; a Analytical Development and Quality Control, Pharmaceutical Technical Development Europe, F. Hoffmann-La Roche Ltd. , Basel , Switzerland.
  • Stracke JO; a Analytical Development and Quality Control, Pharmaceutical Technical Development Europe, F. Hoffmann-La Roche Ltd. , Basel , Switzerland.
  • Koulov A; g Analytical Development and Quality Control, Lonza AG , Basel , Switzerland.
  • Schnaible V; a Analytical Development and Quality Control, Pharmaceutical Technical Development Europe, F. Hoffmann-La Roche Ltd. , Basel , Switzerland.
MAbs ; 8(5): 928-40, 2016 07.
Article em En | MEDLINE | ID: mdl-27031922

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Anticorpos Monoclonais Limite: Humans Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Anticorpos Monoclonais Limite: Humans Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça País de publicação: Estados Unidos