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Synthesis of C-5a-substituted derivatives of 4-epi-isofagomine: notable ß-galactosidase inhibitors and activity promotors of GM1-gangliosidosis related human lysosomal ß-galactosidase mutant R201C.
Thonhofer, Martin; Weber, Patrick; Gonzalez Santana, Andres; Tysoe, Christina; Fischer, Roland; Pabst, Bettina M; Paschke, Eduard; Schalli, Michael; Stütz, Arnold E; Tschernutter, Marion; Windischhofer, Werner; Withers, Stephen G.
Afiliação
  • Thonhofer M; Glycogroup, Institute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, A-8010 Graz, Austria.
  • Weber P; Glycogroup, Institute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, A-8010 Graz, Austria.
  • Gonzalez Santana A; Chemistry Department, University of British Columbia, 2036 Main Mall, Vancouver, BC, Canada V6T 1Z1.
  • Tysoe C; Chemistry Department, University of British Columbia, 2036 Main Mall, Vancouver, BC, Canada V6T 1Z1.
  • Fischer R; Institute of Inorganic Chemistry, Graz University of Technology, Stremayrgasse 9, A-8010 Graz, Austria.
  • Pabst BM; Department of Pediatrics, Laboratory of Metabolic Diseases, MedUni Graz, Auenbruggerplatz 30, A-8036 Graz, Austria.
  • Paschke E; Department of Pediatrics, Laboratory of Metabolic Diseases, MedUni Graz, Auenbruggerplatz 30, A-8036 Graz, Austria.
  • Schalli M; Glycogroup, Institute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, A-8010 Graz, Austria.
  • Stütz AE; Glycogroup, Institute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, A-8010 Graz, Austria. Electronic address: stuetz@tugraz.at.
  • Tschernutter M; Department of Pediatrics, Laboratory of Metabolic Diseases, MedUni Graz, Auenbruggerplatz 30, A-8036 Graz, Austria.
  • Windischhofer W; Department of Pediatrics, Laboratory of Metabolic Diseases, MedUni Graz, Auenbruggerplatz 30, A-8036 Graz, Austria.
  • Withers SG; Chemistry Department, University of British Columbia, 2036 Main Mall, Vancouver, BC, Canada V6T 1Z1.
Carbohydr Res ; 429: 71-80, 2016 Jun 24.
Article em En | MEDLINE | ID: mdl-27063389
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Beta-Galactosidase / 1-Desoxinojirimicina / Imino Piranoses Limite: Humans Idioma: En Revista: Carbohydr Res Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Áustria País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Beta-Galactosidase / 1-Desoxinojirimicina / Imino Piranoses Limite: Humans Idioma: En Revista: Carbohydr Res Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Áustria País de publicação: Holanda