Deguelin-induced blockade of PI3K/protein kinase B/MAP kinase signaling in zebrafish and breast cancer cell lines is mediated by down-regulation of fibroblast growth factor receptor 4 activity.

Wu, Wei; Hai, Yang; Chen, Lu; Liu, Rui-Jin; Han, Yu-Xiang; Li, Wen-Hao; Li, Song; Lin, Shuo; Wu, Xin-Rong

Wu, Wei; Hai, Yang; Chen, Lu; Liu, Rui-Jin; Han, Yu-Xiang; Li, Wen-Hao; Li, Song; Lin, Shuo; Wu, Xin-Rong.

Afiliação

Wu W; Department of Pharmacy Guangzhou Liu Hua Qiao Hospital 111 Liuhua Road Guangzhou Guangdong 510010 China.
Hai Y; Department of Pharmacy Guangzhou Liu Hua Qiao Hospital 111 Liuhua Road Guangzhou Guangdong 510010 China.
Chen L; School of Chemical Biology and Biotechnology Peking University Shenzhen Graduate School Shenzhen Guangdong 518055 China.
Liu RJ; Department of Pharmacy Guangzhou Liu Hua Qiao Hospital 111 Liuhua Road Guangzhou Guangdong 510010 China.
Han YX; School of Chemical Biology and Biotechnology Peking University Shenzhen Graduate School Shenzhen Guangdong 518055 China.
Li WH; Department of Pharmacy Guangzhou Liu Hua Qiao Hospital 111 Liuhua Road Guangzhou Guangdong 510010 China.
Li S; School of Chemical Biology and Biotechnology Peking University Shenzhen Graduate School Shenzhen Guangdong 518055 China.
Lin S; School of Chemical Biology and Biotechnology Peking University Shenzhen Graduate School Shenzhen Guangdong 518055 China; Department of Molecular Cell and Developmental Biology University of California Los Angeles California 90095 USA.
Wu XR; Department of Pharmacy Guangzhou Liu Hua Qiao Hospital 111 Liuhua Road Guangzhou Guangdong 510010 China.

Pharmacol Res Perspect ; 4(2): e00212, 2016 04.

Article em En | MEDLINE | ID: mdl-27069628

Palavras-chave

Breast cancer; FGFR4; deguelin; zebrafish

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Pharmacol Res Perspect Ano de publicação: 2016 Tipo de documento: Article País de publicação: Estados Unidos

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