Oxime-mediated in vitro reactivation kinetic analysis of organophosphates-inhibited human and electric eel acetylcholinesterase.

Sahu, Arvind Kumar; Sharma, Rahul; Gupta, Bhanushree; Musilek, Kamil; Kuca, Kamil; Acharya, Jyotiranjan; Ghosh, Kallol K

Sahu, Arvind Kumar; Sharma, Rahul; Gupta, Bhanushree; Musilek, Kamil; Kuca, Kamil; Acharya, Jyotiranjan; Ghosh, Kallol K.

Afiliação

Sahu AK; a School of Studies in Chemistry, Pt. Ravishankar Shukla University , Raipur , India .
Sharma R; a School of Studies in Chemistry, Pt. Ravishankar Shukla University , Raipur , India .
Gupta B; a School of Studies in Chemistry, Pt. Ravishankar Shukla University , Raipur , India .
Musilek K; b Department of Chemistry , Faculty of Science, University of Hradec Kralove , Hradec Kralove , Czech Republic .
Kuca K; c Biomedical Research Center, University Hospital , Hradec Kralove , Czech Republic , and.
Acharya J; d Process Technology Development Division, Defence Research & Development Establishment , Gwalior, Madhya Pradesh , India.
Ghosh KK; a School of Studies in Chemistry, Pt. Ravishankar Shukla University , Raipur , India .

Toxicol Mech Methods ; 26(5): 319-26, 2016 Jun.

Article em En | MEDLINE | ID: mdl-27101948

Assuntos

Acetilcolinesterase/metabolismo; Inibidores da Colinesterase/farmacologia; Reativadores da Colinesterase/farmacologia; Membrana Eritrocítica/enzimologia; Organofosfatos/farmacologia; Oximas/farmacologia; Adulto; Animais; Relação Dose-Resposta a Droga; Electrophorus; Membrana Eritrocítica/efeitos dos fármacos; Humanos; Cinética; Masculino; Fatores de Tempo

Palavras-chave

Acetylcholinesterase; nerve agents; organophosphate; oxime; pesticides; reactivation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oximas / Organofosfatos / Acetilcolinesterase / Inibidores da Colinesterase / Reativadores da Colinesterase / Membrana Eritrocítica Limite: Adult / Animals / Humans / Male Idioma: En Revista: Toxicol Mech Methods Assunto da revista: TOXICOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Índia

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