Eicosapentaenoic acid attenuates dexamethasome-induced apoptosis by inducing adaptive autophagy via GPR120 in murine bone marrow-derived mesenchymal stem cells.

Gao, B; Han, Y-H; Wang, L; Lin, Y-J; Sun, Z; Lu, W-G; Hu, Y-Q; Li, J-Q; Lin, X-S; Liu, B-H; Jie, Q; Yang, L; Luo, Z-J

Gao, B; Han, Y-H; Wang, L; Lin, Y-J; Sun, Z; Lu, W-G; Hu, Y-Q; Li, J-Q; Lin, X-S; Liu, B-H; Jie, Q; Yang, L; Luo, Z-J.

Afiliação

Gao B; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Han YH; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Wang L; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Lin YJ; Department of Orthopedic Surgery, First Affiliated Hospital, Chengdu Medical College, Chengdu, People's Republic of China.
Sun Z; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Lu WG; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Hu YQ; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Li JQ; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Lin XS; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Liu BH; Health Science Center, Shenzhen University, 3688 Nanhai Ave, Shenzhen 518060, People's Republic of China.
Jie Q; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Yang L; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Luo ZJ; Institute of Orthopedic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.

Cell Death Dis ; 7: e2235, 2016 05 26.

Article em En | MEDLINE | ID: mdl-27228350

Assuntos

Autofagia/efeitos dos fármacos; Dexametasona/antagonistas & inibidores; Ácido Eicosapentaenoico/farmacologia; Células-Tronco Mesenquimais/efeitos dos fármacos; Receptores Acoplados a Proteínas G/genética; Proteínas Quinases Ativadas por AMP/genética; Proteínas Quinases Ativadas por AMP/metabolismo; Animais; Apoptose/efeitos dos fármacos; Ácido Araquidônico/farmacologia; Células da Medula Óssea/citologia; Células da Medula Óssea/efeitos dos fármacos; Células da Medula Óssea/metabolismo; Sobrevivência Celular/efeitos dos fármacos; Dexametasona/farmacologia; Feminino; Regulação da Expressão Gênica; Células-Tronco Mesenquimais/citologia; Células-Tronco Mesenquimais/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Cultura Primária de Células; Receptores Acoplados a Proteínas G/metabolismo; Transdução de Sinais; Serina-Treonina Quinases TOR/genética; Serina-Treonina Quinases TOR/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Dexametasona / Ácido Eicosapentaenoico / Receptores Acoplados a Proteínas G / Células-Tronco Mesenquimais Limite: Animals Idioma: En Revista: Cell Death Dis Ano de publicação: 2016 Tipo de documento: Article País de publicação: Reino Unido

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