Recurrent neonatal herpes presenting initially with hoarseness.
Am J Perinatol
; 6(3): 307-9, 1989 Jul.
Article
em En
| MEDLINE
| ID: mdl-2730736
ABSTRACT
This report describes a newborn with recurrent herpes simplex meningoencephalitis despite vigorous antiviral therapy. The course is unusual in that the presenting symptom was hoarseness. Despite probable adequate acyclovir levels in the spinal fluid, a second episode or progression of herpetic encephalitis occurred, suggesting impairment of host defenses, particularly cellular immunity. This episode was treated with both acyclovir and vidarabine. Pharmacokinetics of the antiviral therapy and immune responses are discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Rouquidão
/
Herpes Simples
/
Meningoencefalite
Limite:
Humans
/
Male
/
Newborn
Idioma:
En
Revista:
Am J Perinatol
Ano de publicação:
1989
Tipo de documento:
Article