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Investigation of the Brain Biodistribution of the Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitor [18F]GSK2647544 in Healthy Male Subjects.
Huiban, Mickael; Coello, Christopher; Wu, Kai; Xu, Yanmei; Lewis, Yvonne; Brown, Andrew P; Buraglio, Mauro; Guan, Chenbing; Shabbir, Shaila; Fong, Regan; Passchier, Jan; Rabiner, Eugenii A; Lockhart, Andrew.
Afiliação
  • Huiban M; Imanova Limited, Burlington Danes Building, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.
  • Coello C; Imanova Limited, Burlington Danes Building, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.
  • Wu K; WuXi Clinical Development Service, 19th Floor, Building A, FuXing Plaza, 388 Ma Dang Road, Shanghai, 200025, China.
  • Xu Y; GlaxoSmithKline, Neurosciences, 917 Halei Road, Zhangjiang Hi-tech Park, Pudong, Shanghai, 201203, China.
  • Lewis Y; Imanova Limited, Burlington Danes Building, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.
  • Brown AP; AstraZeneca UK Limited, Melbourn Science Park, Royston, Herts, SG8 6HB, UK.
  • Buraglio M; GlaxoSmithKline, Neurosciences, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
  • Guan C; GlaxoSmithKline, Neurosciences, 917 Halei Road, Zhangjiang Hi-tech Park, Pudong, Shanghai, 201203, China.
  • Shabbir S; GlaxoSmithKline, Neurosciences, Gunnels Wood Road, Stevenage, SG1 2NY, UK.
  • Fong R; UCB Biosciences Inc, PO Box 110167, Research Triangle Park, NC, 27709, USA.
  • Passchier J; Imanova Limited, Burlington Danes Building, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.
  • Rabiner EA; Imanova Limited, Burlington Danes Building, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.
  • Lockhart A; GlaxoSmithKline, Neurosciences, Clinical Unit Cambridge, Addenbrooke's Hospital, Cambridge, CB2 0GG, UK. andrew.2.lockhart@gsk.com.
Mol Imaging Biol ; 19(1): 153-161, 2017 02.
Article em En | MEDLINE | ID: mdl-27402093
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Éteres Fenílicos / Pirimidinonas / Encéfalo / Radioisótopos de Flúor / 1-Alquil-2-acetilglicerofosfocolina Esterase Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Animals / Humans / Male / Middle aged Idioma: En Revista: Mol Imaging Biol Assunto da revista: BIOLOGIA MOLECULAR / DIAGNOSTICO POR IMAGEM Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Éteres Fenílicos / Pirimidinonas / Encéfalo / Radioisótopos de Flúor / 1-Alquil-2-acetilglicerofosfocolina Esterase Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Animals / Humans / Male / Middle aged Idioma: En Revista: Mol Imaging Biol Assunto da revista: BIOLOGIA MOLECULAR / DIAGNOSTICO POR IMAGEM Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido