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Leukemia in Patients with Klinefelter Syndrome: A Report of Two Cases.
Bchir, M; Ayed, W; Neji, H Ben; Kilani, O; Kefi, S; Zarrouk, M; Guermani, H; Hentati, S; Amouri, A; Meddeb, B.
Afiliação
  • Bchir M; Department of Hematology, Aziza Othmana University Hospital, Place du gouvernement, la Kasbbah, 1008 Tunis, Tunisia.
  • Ayed W; Laboratory of Histology and Cytogenetics, Department of Histology and Cytogenetics, Faculty of Medicine of Tunis, Institut Pasteur de Tunis, El Manar Tunis University, 13, Place Pasteur, BP74, 1002 Tunis, Tunisia.
  • Neji HB; Department of Hematology, Aziza Othmana University Hospital, Place du gouvernement, la Kasbbah, 1008 Tunis, Tunisia.
  • Kilani O; Laboratory of Histology and Cytogenetics, Department of Histology and Cytogenetics, Faculty of Medicine of Tunis, Institut Pasteur de Tunis, El Manar Tunis University, 13, Place Pasteur, BP74, 1002 Tunis, Tunisia.
  • Kefi S; Department of Hematology, Aziza Othmana University Hospital, Place du gouvernement, la Kasbbah, 1008 Tunis, Tunisia.
  • Zarrouk M; Department of Hematology, Aziza Othmana University Hospital, Place du gouvernement, la Kasbbah, 1008 Tunis, Tunisia.
  • Guermani H; Laboratory of Histology and Cytogenetics, Department of Histology and Cytogenetics, Faculty of Medicine of Tunis, Institut Pasteur de Tunis, El Manar Tunis University, 13, Place Pasteur, BP74, 1002 Tunis, Tunisia.
  • Hentati S; Laboratory of Histology and Cytogenetics, Department of Histology and Cytogenetics, Faculty of Medicine of Tunis, Institut Pasteur de Tunis, El Manar Tunis University, 13, Place Pasteur, BP74, 1002 Tunis, Tunisia.
  • Amouri A; Laboratory of Histology and Cytogenetics, Department of Histology and Cytogenetics, Faculty of Medicine of Tunis, Institut Pasteur de Tunis, El Manar Tunis University, 13, Place Pasteur, BP74, 1002 Tunis, Tunisia.
  • Meddeb B; Department of Hematology, Aziza Othmana University Hospital, Place du gouvernement, la Kasbbah, 1008 Tunis, Tunisia.
Indian J Hematol Blood Transfus ; 32(Suppl 1): 66-8, 2016 Jun.
Article em En | MEDLINE | ID: mdl-27408358
Klinefelter syndrome (KS) is a chromosome abnormality characterized by a 47, XXY karyotype associated with hypogonadism and infertility. We present two cases of leukemia in patients with KS. The first patient presented with acute promyelocytic leukemia. He relapsed after the end of treatment. The second patient was diagnosed with chronic myeloid leukemia. Treatment with imatinib failed and the patient presented with myeloid blast crisis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Indian J Hematol Blood Transfus Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Tunísia País de publicação: Índia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Indian J Hematol Blood Transfus Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Tunísia País de publicação: Índia