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Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor.
Martínez-Hoyos, María; Perez-Herran, Esther; Gulten, Gulcin; Encinas, Lourdes; Álvarez-Gómez, Daniel; Alvarez, Emilio; Ferrer-Bazaga, Santiago; García-Pérez, Adolfo; Ortega, Fátima; Angulo-Barturen, Iñigo; Rullas-Trincado, Joaquin; Blanco Ruano, Delia; Torres, Pedro; Castañeda, Pablo; Huss, Sophie; Fernández Menéndez, Raquel; González Del Valle, Silvia; Ballell, Lluis; Barros, David; Modha, Sundip; Dhar, Neeraj; Signorino-Gelo, François; McKinney, John D; García-Bustos, Jose Francisco; Lavandera, Jose Luis; Sacchettini, James C; Jimenez, M Soledad; Martín-Casabona, Nuria; Castro-Pichel, Julia; Mendoza-Losana, Alfonso.
Afiliação
  • Martínez-Hoyos M; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Perez-Herran E; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Gulten G; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
  • Encinas L; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Álvarez-Gómez D; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Alvarez E; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Ferrer-Bazaga S; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • García-Pérez A; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Ortega F; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Angulo-Barturen I; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Rullas-Trincado J; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Blanco Ruano D; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Torres P; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Castañeda P; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Huss S; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Fernández Menéndez R; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • González Del Valle S; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Ballell L; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Barros D; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Modha S; Target and Pathway Validation, Molecular Discovery Research, GlaxoSmithKline, Stevenage, Herts, UK.
  • Dhar N; School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), Lausanne 1015, Switzerland.
  • Signorino-Gelo F; Target and Pathway Validation, Molecular Discovery Research, GlaxoSmithKline, Stevenage, Herts, UK.
  • McKinney JD; Target and Pathway Validation, Molecular Discovery Research, GlaxoSmithKline, Stevenage, Herts, UK.
  • García-Bustos JF; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Lavandera JL; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Sacchettini JC; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
  • Jimenez MS; ISCIII, Crta. Majadahonda-Pozuelo Km 2, Majadahonda 28220, Madrid.
  • Martín-Casabona N; Department of Microbiology Vall d'Hebron Hospital, Autonomous University Barcelona, Barcelona, Spain.
  • Castro-Pichel J; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
  • Mendoza-Losana A; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain. Electronic address: alfonso.x.mendoza@gsk.com.
EBioMedicine ; 8: 291-301, 2016 Jun.
Article em En | MEDLINE | ID: mdl-27428438
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Enoil-(Proteína de Transporte de Acila) Redutase (NADH) / Mycobacterium tuberculosis / Antituberculosos Limite: Animals / Female / Humans Idioma: En Revista: EBioMedicine Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Espanha País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Enoil-(Proteína de Transporte de Acila) Redutase (NADH) / Mycobacterium tuberculosis / Antituberculosos Limite: Animals / Female / Humans Idioma: En Revista: EBioMedicine Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Espanha País de publicação: Holanda