4-aroylpiperidines and 4-(&#945;-hydroxyphenyl)piperidines as selective sigma-1 receptor ligands: synthesis, preliminary pharmacological evaluation and computational studies.

Ikome, Hermia N; Ntie-Kang, Fidele; Ngemenya, Moses N; Tu, Zhude; Mach, Robert H; Efange, Simon M N

4-aroylpiperidines and 4-(α-hydroxyphenyl)piperidines as selective sigma-1 receptor ligands: synthesis, preliminary pharmacological evaluation and computational studies.

Ikome, Hermia N; Ntie-Kang, Fidele; Ngemenya, Moses N; Tu, Zhude; Mach, Robert H; Efange, Simon M N.

Afiliação

Ikome HN; Department of Chemistry, Faculty of Science, University of Buea, P.O. Box 63, Buea, South West Region Cameroon.
Ntie-Kang F; Department of Chemistry, Faculty of Science, University of Buea, P.O. Box 63, Buea, South West Region Cameroon ; Department of Pharmaceutical Chemistry, Martin-Luther University of Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, 06120 Halle (Saale), Germany.
Ngemenya MN; Biotechnology Unit, Department of Biochemistry and Molecular Biology, Faculty of Science, University of Buea, P.O.Box 63, Buea, South West Region Cameroon.
Tu Z; Department of Radiology, University of Washington School of Medicine, Seattle, USA.
Mach RH; Department of Radiology, University of Washington School of Medicine, Seattle, USA.
Efange SM; Department of Chemistry, Faculty of Science, University of Buea, P.O. Box 63, Buea, South West Region Cameroon.

Chem Cent J ; 10(1): 53, 2016.

Article em En | MEDLINE | ID: mdl-27555879

Palavras-chave

Pharmacophore; Piperidines; QSAR; Sigma-1 binding

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Chem Cent J Ano de publicação: 2016 Tipo de documento: Article País de publicação: Reino Unido

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google