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Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A).
Choi, Junjeong; Lee, Ji-Hyun; Koh, Ilkyoo; Shim, Jin-Kyoung; Park, Junseong; Jeon, Jeong Yong; Yun, Mijin; Kim, Se Hoon; Yook, Jong In; Kim, Eui Hyun; Chang, Jong Hee; Kim, Sun Ho; Huh, Yong Min; Lee, Su Jae; Pollak, Michael; Kim, Pilnam; Kang, Seok-Gu; Cheong, Jae-Ho.
Afiliação
  • Choi J; Department of Pharmacy, College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea.
  • Lee JH; Brain Korea 21 Plus Project for Medical Science, Yonsei University, Seoul, Republic of Korea.
  • Koh I; Departments of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Shim JK; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
  • Park J; Departments of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Jeon JY; Departments of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Yun M; Departments of Nuclear Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Kim SH; Departments of Nuclear Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Yook JI; Departments of Pathology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Kim EH; Department of Oral Pathology, Yonsei University College of Dentistry, Seoul, Republic of Korea.
  • Chang JH; Departments of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Kim SH; Departments of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Huh YM; Departments of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Lee SJ; Departments of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Pollak M; Department of Life Science, Research Institute for Natural Sciences, Hanyang University, Seoul, Republic of Korea.
  • Kim P; Department of Oncology and Medicine, McGill University, Gerald Bronfman Centre, Montreal, Quebec, Canada.
  • Kang SG; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
  • Cheong JH; Departments of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Oncotarget ; 7(40): 65643-65659, 2016 10 04.
Article em En | MEDLINE | ID: mdl-27582539
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolidinas / Células-Tronco Neoplásicas / Neoplasias Encefálicas / Regulação Neoplásica da Expressão Gênica / Glioblastoma / Antineoplásicos Alquilantes / Dacarbazina / Guanidinas Limite: Animals / Humans / Male Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolidinas / Células-Tronco Neoplásicas / Neoplasias Encefálicas / Regulação Neoplásica da Expressão Gênica / Glioblastoma / Antineoplásicos Alquilantes / Dacarbazina / Guanidinas Limite: Animals / Humans / Male Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article