Evidence of dipstick superiority over urine microscopy analysis for detection of hematuria.
BMC Res Notes
; 9(1): 435, 2016 Sep 08.
Article
em En
| MEDLINE
| ID: mdl-27608628
ABSTRACT
BACKGROUND:
There is an unresolved debate on the best screening method for hematuria as a symptom of glomerulonephritis or urological malignancies. The urinary dipstick is generally considered as an imperfect surrogate for urine microscopy analysis.RESULTS:
We designed a study to compare urine microscopy analysis, urinary dipstick and flow cytometry, using controlled dilutions of blood in urine samples from volunteers collected in two different physiologically-relevant conditions (basal state and hyperhydration). We found that although all techniques were 100 % effective in detecting hematuria at basal state, these results were variably reproduced when testing the same final amount of hematuria in urine collected after hyperhydration. Our data shows a variable sensitivity for the detection of hematuria by urine microscopy analysis or flow cytometry, but not by urinary dipstick.CONCLUSIONS:
Urinary dipstick qualifies as a better screening test for hematuria than urine microscopy analysis or flow cytometry, as it is sensitive and performs better in unstandardized conditions. It is universally available and also faster and cheaper than cytometric techniques.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Urinálise
/
Hematúria
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
BMC Res Notes
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
França