[Patterns in the combined action of irradiation and glucose loading on tumor cells]. / Zakonomernosti kombinirovannogo deistviia oblucheniia i gliukoznoi nagruzki na opukholevye kletki.

ABSTRACT

It was shown that incubation of Ehrlich ascites tumor cells with glucose or in buffer solutions of low pH decreases their viability. The cell survival rate depends on pH values irrespective of the protoxidation method and oxygenation conditions used. At the same time, radiosensitivity of Ehrlich ascites tumor cells is practically invariable with pH being decreased from 7.0 to 5.0. The effects of glucose and radiation are additive in conditions simulating the effect of hyperglycaemia in vivo.