Identification of small molecules that bind to the mitochondrial protein mitoNEET.

Geldenhuys, Werner J; Yonutas, Heather M; Morris, Daniel L; Sullivan, Patrick G; Darvesh, Altaf S; Leeper, Thomas C

Geldenhuys, Werner J; Yonutas, Heather M; Morris, Daniel L; Sullivan, Patrick G; Darvesh, Altaf S; Leeper, Thomas C.

Afiliação

Geldenhuys WJ; Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 1 Medical Center Drive, Morgantown, WV 26506, USA. Electronic address: werner.geldenhuys@hsc.wvu.edu.
Yonutas HM; Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40536, USA; Anatomy and Neurobiology, University of Kentucky, Lexington, KY 40536, USA.
Morris DL; Department of Chemistry and Biochemistry, University of Akron, Akron, OH 44325, USA.
Sullivan PG; Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40536, USA; Anatomy and Neurobiology, University of Kentucky, Lexington, KY 40536, USA.
Darvesh AS; Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, OH 44240, USA.
Leeper TC; Department of Chemistry and Biochemistry, University of Akron, Akron, OH 44325, USA.

Bioorg Med Chem Lett ; 26(21): 5350-5353, 2016 11 01.

Article em En | MEDLINE | ID: mdl-27687671

Assuntos

Proteínas Mitocondriais/metabolismo; Bibliotecas de Moléculas Pequenas; Hipoglicemiantes/química; Hipoglicemiantes/metabolismo; Ligantes; Ligação Proteica; Tiazolidinedionas/química; Tiazolidinedionas/metabolismo

Palavras-chave

Bioenergetics; Glitazones; Mitochondria; Type II diabetes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Mitocondriais / Bibliotecas de Moléculas Pequenas Tipo de estudo: Diagnostic_studies Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article

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