Vitamin E protects rat mesenchymal stem cells against hydrogen peroxide-induced oxidative stress in vitro and improves their therapeutic potential in surgically-induced rat model of osteoarthritis.

Bhatti, F U; Mehmood, A; Latief, N; Zahra, S; Cho, H; Khan, S N; Riazuddin, S

Vitamin E protects rat mesenchymal stem cells against hydrogen peroxide-induced oxidative stress in vitro and improves their therapeutic potential in surgically-induced rat model of osteoarthritis.

Bhatti, F U; Mehmood, A; Latief, N; Zahra, S; Cho, H; Khan, S N; Riazuddin, S.

Afiliação

Bhatti FU; National Centre of Excellence in Molecular Biology, 87-West Canal Bank Road, University of the Punjab, Lahore, Pakistan; University of Tennessee Health Science Center-Campbell Clinic, Memphis, TN, USA. Electronic address: fbhatti@uthsc.edu.
Mehmood A; National Centre of Excellence in Molecular Biology, 87-West Canal Bank Road, University of the Punjab, Lahore, Pakistan. Electronic address: azra_mehmood@hotmail.com.
Latief N; National Centre of Excellence in Molecular Biology, 87-West Canal Bank Road, University of the Punjab, Lahore, Pakistan. Electronic address: noreenlatief@gmail.com.
Zahra S; National Centre of Excellence in Molecular Biology, 87-West Canal Bank Road, University of the Punjab, Lahore, Pakistan. Electronic address: sanazaahra@gmail.com.
Cho H; University of Tennessee Health Science Center-Campbell Clinic, Memphis, TN, USA; Veterans Affairs Medical Center, Memphis, TN, USA. Electronic address: hcho4@uthsc.edu.
Khan SN; National Centre of Excellence in Molecular Biology, 87-West Canal Bank Road, University of the Punjab, Lahore, Pakistan. Electronic address: snkhan50@yahoo.com.
Riazuddin S; National Centre of Excellence in Molecular Biology, 87-West Canal Bank Road, University of the Punjab, Lahore, Pakistan; Allama Iqbal Medical College, University of Health Sciences, Lahore, Pakistan. Electronic address: riazuddin@aimrc.org.

Osteoarthritis Cartilage ; 25(2): 321-331, 2017 02.

Article em En | MEDLINE | ID: mdl-27693502

Assuntos

Células-Tronco Mesenquimais/efeitos dos fármacos; Osteoartrite/tratamento farmacológico; Estresse Oxidativo/efeitos dos fármacos; Vitamina E/farmacologia; Animais; Apoptose/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Condrogênese/efeitos dos fármacos; Modelos Animais de Doenças; Feminino; Peróxido de Hidrogênio/farmacologia; Técnicas In Vitro; Células-Tronco Mesenquimais/metabolismo; Ratos; Ratos Sprague-Dawley; Vitamina E/uso terapêutico

Palavras-chave

Antioxidant; Mesenchymal stem cells; Osteoarthritis; Oxidative stress; Vitamin E

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Vitamina E / Estresse Oxidativo / Células-Tronco Mesenquimais Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Osteoarthritis Cartilage Assunto da revista: ORTOPEDIA / REUMATOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido

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