Mechanisms of Tubulin Binding Ligands to Target Cancer Cells: Updates on their Therapeutic Potential and Clinical Trials.

Kumar, Bhupinder; Kumar, Rakesh; Skvortsova, Ira; Kumar, Vinod

Kumar, Bhupinder; Kumar, Rakesh; Skvortsova, Ira; Kumar, Vinod.

Afiliação

Kumar B; Laboratory of Organic and Medicinal Chemistry, Centre for Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda, Punjab, India.
Kumar R; Laboratory of Organic Chemistry, Centre for Chemical Sciences, Central University of Punjab, Bathinda, Punjab, India.
Skvortsova I; Laboratory for Experimental and Translational Research on Radiation Oncology (EXTRO-Lab), Department of Therapeutic Radiology and Oncology, Innsbruck Medical University, Anichstr. 35, A-6020 Innsbruck. Austria.
Kumar V; Laboratory of Organic and Medicinal Chemistry, Centre for Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda, Punjab, India.

Curr Cancer Drug Targets ; 17(4): 357-375, 2017.

Article em En | MEDLINE | ID: mdl-27697026

Assuntos

Neoplasias/tratamento farmacológico; Tubulina (Proteína)/metabolismo; Sítios de Ligação; Humanos; Ligantes; Microtúbulos/efeitos dos fármacos; Neoplasias/patologia; Polimerização

Palavras-chave

Tubulin inhibitor; anticancer; combination therapy; microtubule stabilizing agents; tubulin binding ligands; tubulin polymerization/depolymerization

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Neoplasias Limite: Humans Idioma: En Revista: Curr Cancer Drug Targets Assunto da revista: ANTINEOPLASICOS / NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Índia País de publicação: Holanda

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