Nuclease activity as a specific biomarker for breast cancer.
Chem Commun (Camb)
; 52(83): 12346-12349, 2016 Oct 25.
Article
em En
| MEDLINE
| ID: mdl-27722495
ABSTRACT
We report on the activity of nucleases derived from cancer cells as a means for specific targeting using nucleic acid probes (substrates). We hypothesize that cancer cells can be differentiated from healthy cells based on their nuclease activity profile, and thus, any method based on this property represents a novel alternative for diagnostic and therapeutic intervention.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
/
Sondas de Ácido Nucleico
/
Biomarcadores Tumorais
/
Desoxirribonucleases
Limite:
Female
/
Humans
Idioma:
En
Revista:
Chem Commun (Camb)
Assunto da revista:
QUIMICA
Ano de publicação:
2016
Tipo de documento:
Article