Modulation of serotonin transporter function by kappa-opioid receptor ligands.

Sundaramurthy, Santhanalakshmi; Annamalai, Balasubramaniam; Samuvel, Devadoss J; Shippenberg, Toni S; Jayanthi, Lankupalle D; Ramamoorthy, Sammanda

Sundaramurthy, Santhanalakshmi; Annamalai, Balasubramaniam; Samuvel, Devadoss J; Shippenberg, Toni S; Jayanthi, Lankupalle D; Ramamoorthy, Sammanda.

Afiliação

Sundaramurthy S; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA 23298, USA.
Annamalai B; Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA.
Samuvel DJ; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Shippenberg TS; Integrative Neuroscience Section, National Institutes of Health, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD 21224, USA.
Jayanthi LD; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA 23298, USA.
Ramamoorthy S; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA 23298, USA. Electronic address: sammanda.ramamoorthy@vcuhealth.org.

Neuropharmacology ; 113(Pt A): 281-292, 2017 02.

Article em En | MEDLINE | ID: mdl-27743931

Assuntos

Analgésicos Opioides/farmacologia; Antagonistas de Entorpecentes/farmacologia; Receptores Opioides kappa/agonistas; Receptores Opioides kappa/antagonistas & inibidores; Proteínas da Membrana Plasmática de Transporte de Serotonina/fisiologia; Analgésicos Opioides/metabolismo; Animais; Endocitose/efeitos dos fármacos; Endocitose/fisiologia; Células HEK293; Humanos; Ligantes; Masculino; Antagonistas de Entorpecentes/metabolismo; Ratos; Ratos Sprague-Dawley; Receptores Opioides kappa/metabolismo; Serotonina/metabolismo; Serotonina/farmacologia

Palavras-chave

Clearance; Kappa opioid receptor; Phosphorylation; Serotonin; Serotonin transporter; Trafficking

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Opioides kappa / Proteínas da Membrana Plasmática de Transporte de Serotonina / Analgésicos Opioides / Antagonistas de Entorpecentes Limite: Animals / Humans / Male Idioma: En Revista: Neuropharmacology Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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