Structural Dynamics in Ras and Related Proteins upon Nucleotide Switching.

Harrison, Rane A; Lu, Jia; Carrasco, Martin; Hunter, John; Manandhar, Anuj; Gondi, Sudershan; Westover, Kenneth D; Engen, John R

Harrison, Rane A; Lu, Jia; Carrasco, Martin; Hunter, John; Manandhar, Anuj; Gondi, Sudershan; Westover, Kenneth D; Engen, John R.

Afiliação

Harrison RA; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.
Lu J; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Carrasco M; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Hunter J; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Manandhar A; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Gondi S; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Westover KD; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: kenneth.westover@utsouthwestern.edu.
Engen JR; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA. Electronic address: j.engen@northeastern.edu.

J Mol Biol ; 428(23): 4723-4735, 2016 11 20.

Article em En | MEDLINE | ID: mdl-27751724

Assuntos

Nucleotídeos/metabolismo; Proteínas ras/química; Proteínas ras/metabolismo; Proteínas rho de Ligação ao GTP/química; Proteínas rho de Ligação ao GTP/metabolismo; Animais; Humanos; Espectrometria de Massas; Simulação de Dinâmica Molecular

Palavras-chave

Rho; guanosine diphosphate (GDP); hydrogendeuterium exchange mass spectrometry; protein dynamics; signal transduction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas ras / Proteínas rho de Ligação ao GTP / Nucleotídeos Limite: Animals / Humans Idioma: En Revista: J Mol Biol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Holanda

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