Presence of the Merkel cell polyomavirus in Merkel cell carcinoma combined with squamous cell carcinoma in a patient with chronic arsenism.
Clin Exp Dermatol
; 41(8): 902-905, 2016 Dec.
Article
em En
| MEDLINE
| ID: mdl-27774637
ABSTRACT
We present a case of Merkel cell carcinoma (MCC) coincident with squamous cell carcinoma (SCC) on the breast of a woman with chronic arsenism. This case demonstrates the distinct association of chronic arsenism with two different primary cutaneous carcinomas. Merkel cell polyomavirus (MCPyV) was identified in the lesional skin of the MCC but not in that of the SCC, suggesting there are different interactions of MCPyV in the pathogenesis of SCC and MCC related to arsenic. Physicians need to be vigilant in the occurrence of both SCC and MCC in patients with chronic arsenism. To our knowledge, this is the first study to show the presence of MCPyV in the MCC but not the SCC portion of an arsenic-induced tumour.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arsênio
/
Neoplasias Cutâneas
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Infecções Tumorais por Vírus
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Doença de Bowen
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Neoplasias da Mama
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Carcinoma de Células Escamosas
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Carcinoma de Célula de Merkel
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Infecções por Polyomavirus
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Poliomavírus das Células de Merkel
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Neoplasias Primárias Múltiplas
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Clin Exp Dermatol
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Taiwan