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Translating genome-wide association findings into new therapeutics for psychiatry.
Breen, Gerome; Li, Qingqin; Roth, Bryan L; O'Donnell, Patricio; Didriksen, Michael; Dolmetsch, Ricardo; O'Reilly, Paul F; Gaspar, Héléna A; Manji, Husseini; Huebel, Christopher; Kelsoe, John R; Malhotra, Dheeraj; Bertolino, Alessandro; Posthuma, Danielle; Sklar, Pamela; Kapur, Shitij; Sullivan, Patrick F; Collier, David A; Edenberg, Howard J.
Afiliação
  • Breen G; MRC Social, Genetic &Developmental Psychiatry Centre, Institute of Psychiatry, Psychology &Neuroscience, King's College London, London, UK.
  • Li Q; UK National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health, South London and Maudsley Hospital, London, UK.
  • Roth BL; Neuroscience Therapeutic Area, Janssen Research &Development, LLC, Titusville, New Jersey, USA.
  • O'Donnell P; Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Didriksen M; National Institute of Mental Health Psychoactive Drug Screening Program (NIMH PDSP), School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Dolmetsch R; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • O'Reilly PF; Neuroscience Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA.
  • Gaspar HA; H. Lundbeck A/S, Synaptic Transmission, Neuroscience Research DK, Valby, Denmark.
  • Manji H; Department of Neuroscience, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, USA.
  • Huebel C; MRC Social, Genetic &Developmental Psychiatry Centre, Institute of Psychiatry, Psychology &Neuroscience, King's College London, London, UK.
  • Kelsoe JR; MRC Social, Genetic &Developmental Psychiatry Centre, Institute of Psychiatry, Psychology &Neuroscience, King's College London, London, UK.
  • Malhotra D; UK National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health, South London and Maudsley Hospital, London, UK.
  • Bertolino A; Neuroscience Therapeutic Area, Janssen Research &Development, LLC, Titusville, New Jersey, USA.
  • Posthuma D; MRC Social, Genetic &Developmental Psychiatry Centre, Institute of Psychiatry, Psychology &Neuroscience, King's College London, London, UK.
  • Sklar P; UK National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health, South London and Maudsley Hospital, London, UK.
  • Kapur S; Department of Psychiatry, University of California San Diego, and Veterans Affairs San Diego Healthcare System, La Jolla, California, USA.
  • Sullivan PF; Neuroscience Discovery and Translational Area, Pharma Research &Early Development, F. Hoffmann - La Roche, Basel, Switzerland.
  • Collier DA; Institute of Psychiatry, Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy.
  • Edenberg HJ; Department of Complex Trait Genetics, Centre for Neurogenomics and Cognitive Research/VU University Amsterdam, Amsterdam, the Netherlands.
Nat Neurosci ; 19(11): 1392-1396, 2016 10 26.
Article em En | MEDLINE | ID: mdl-27786187
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psiquiatria / Predisposição Genética para Doença / Polimorfismo de Nucleotídeo Único / Estudo de Associação Genômica Ampla / Transtornos Mentais Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Nat Neurosci Assunto da revista: NEUROLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psiquiatria / Predisposição Genética para Doença / Polimorfismo de Nucleotídeo Único / Estudo de Associação Genômica Ampla / Transtornos Mentais Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Nat Neurosci Assunto da revista: NEUROLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos