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ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly.
Ghouzzi, Vincent El; Bianchi, Federico T; Molineris, Ivan; Mounce, Bryan C; Berto, Gaia E; Rak, Malgorzata; Lebon, Sophie; Aubry, Laetitia; Tocco, Chiara; Gai, Marta; Chiotto, Alessandra Ma; Sgrò, Francesco; Pallavicini, Gianmarco; Simon-Loriere, Etienne; Passemard, Sandrine; Vignuzzi, Marco; Gressens, Pierre; Di Cunto, Ferdinando.
Afiliação
  • Ghouzzi VE; PROTECT, INSERM, Unversité Paris Diderot, Sorbonne Paris Cité, Paris, France.
  • Bianchi FT; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Centre, University of Turin, Turin, Italy.
  • Molineris I; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Centre, University of Turin, Turin, Italy.
  • Mounce BC; Institut Pasteur, Centre National de la RechercheScientifique UMR 3569, Viral Populations and Pathogenesis Unit, Paris, France.
  • Berto GE; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Centre, University of Turin, Turin, Italy.
  • Rak M; PROTECT, INSERM, Unversité Paris Diderot, Sorbonne Paris Cité, Paris, France.
  • Lebon S; PROTECT, INSERM, Unversité Paris Diderot, Sorbonne Paris Cité, Paris, France.
  • Aubry L; UEVE UMR 861, I-Stem, AFM, Evry, France.
  • Tocco C; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Centre, University of Turin, Turin, Italy.
  • Gai M; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Centre, University of Turin, Turin, Italy.
  • Chiotto AM; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Centre, University of Turin, Turin, Italy.
  • Sgrò F; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Centre, University of Turin, Turin, Italy.
  • Pallavicini G; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Centre, University of Turin, Turin, Italy.
  • Simon-Loriere E; Institut Pasteur, Functional Genetics of Infectious Diseases Unit, Paris 75724, France.
  • Passemard S; CNRS URA3012, Paris 75015, France.
  • Vignuzzi M; PROTECT, INSERM, Unversité Paris Diderot, Sorbonne Paris Cité, Paris, France.
  • Gressens P; Département de Génétique, Hôpital Robert Debré, Paris, France.
  • Di Cunto F; Institut Pasteur, Centre National de la RechercheScientifique UMR 3569, Viral Populations and Pathogenesis Unit, Paris, France.
Cell Death Dis ; 7(10): e2440, 2016 10 27.
Article em En | MEDLINE | ID: mdl-27787521
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Proteína Supressora de Tumor p53 / Células-Tronco Neurais / Zika virus / Microcefalia / Mutação Limite: Animals / Humans Idioma: En Revista: Cell Death Dis Ano de publicação: 2016 Tipo de documento: Article País de afiliação: França País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Proteína Supressora de Tumor p53 / Células-Tronco Neurais / Zika virus / Microcefalia / Mutação Limite: Animals / Humans Idioma: En Revista: Cell Death Dis Ano de publicação: 2016 Tipo de documento: Article País de afiliação: França País de publicação: Reino Unido