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Significant Effect of Polymorphisms in CYP2D6 on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study.
Zembutsu, Hitoshi; Nakamura, Seigo; Akashi-Tanaka, Sadako; Kuwayama, Takashi; Watanabe, Chie; Takamaru, Tomoko; Takei, Hiroyuki; Ishikawa, Takashi; Miyahara, Kana; Matsumoto, Hiroshi; Hasegawa, Yoshie; Kutomi, Goro; Shima, Hiroaki; Satomi, Fukino; Okazaki, Minoru; Zaha, Hisamitsu; Onomura, Mai; Matsukata, Ayami; Sagara, Yasuaki; Baba, Shinichi; Yamada, Akimitsu; Shimada, Kazuhiro; Shimizu, Daisuke; Tsugawa, Koichiro; Shimo, Arata; Tan, Ern Yu; Hartman, Mikael; Chan, Ching-Wan; Lee, Soo Chin; Nakamura, Yusuke.
Afiliação
  • Zembutsu H; Division of Genetics, National Cancer Center Research Institute, Tokyo, Japan. hzenbuts@ncc.go.jp.
  • Nakamura S; Department of Breast Surgery, Showa University, Tokyo, Japan.
  • Akashi-Tanaka S; Department of Breast Surgery, Showa University, Tokyo, Japan.
  • Kuwayama T; Department of Breast Surgery, Showa University, Tokyo, Japan.
  • Watanabe C; Department of Breast Surgery, Showa University, Tokyo, Japan.
  • Takamaru T; Department of Breast Surgery, Showa University, Tokyo, Japan.
  • Takei H; Department of Breast Surgery, Nippon Medical School, Tokyo, Japan.
  • Ishikawa T; Department of Breast Surgery, Tokyo Medical University, Tokyo, Japan.
  • Miyahara K; Department of Breast Surgery, Tokyo Medical University, Tokyo, Japan.
  • Matsumoto H; Department of Breast Surgery, Saitama Cancer Center, Saitama, Japan.
  • Hasegawa Y; Department of Breast Surgery, Hirosaki Municipal Hospital, Hirosaki, Japan.
  • Kutomi G; 1st Department of Surgery, Sapporo Medical University, Sapporo, Japan.
  • Shima H; 1st Department of Surgery, Sapporo Medical University, Sapporo, Japan.
  • Satomi F; 1st Department of Surgery, Sapporo Medical University, Sapporo, Japan.
  • Okazaki M; Department of Breast Surgery, Sapporo Breast Surgical Clinic, Sapporo, Japan.
  • Zaha H; Department of Breast Surgery, Nakagami Hospital, Okinawa, Japan.
  • Onomura M; Department of Breast Surgery, Nakagami Hospital, Okinawa, Japan.
  • Matsukata A; Department of Breast Surgery, Sagara Hospital, Kagoshima, Japan.
  • Sagara Y; Department of Breast Surgery, Sagara Hospital, Kagoshima, Japan.
  • Baba S; Department of Breast Surgery, Sagara Hospital, Kagoshima, Japan.
  • Yamada A; Department of Breast and Thyroid Surgery, Yokohama City University Medical Center, Yokohama, Japan.
  • Shimada K; Department of Breast and Thyroid Surgery, Yokohama City University Medical Center, Yokohama, Japan.
  • Shimizu D; Department of Breast Surgery, Yokohama Minato Red Cross Hospital, Yokohama, Japan.
  • Tsugawa K; Department of Breast and Endocrine Surgery, St. Marianna University School of Medicine Hospital, Kawasaki, Japan.
  • Shimo A; Department of Breast and Endocrine Surgery, St. Marianna University School of Medicine Hospital, Kawasaki, Japan.
  • Tan EY; Department of General Surgery, Tan Tock Seng Hospital, Singapore.
  • Hartman M; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore.
  • Chan CW; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore.
  • Lee SC; Department of Hematology Oncology, National University Cancer Institute, National University Health System, Singapore.
  • Nakamura Y; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, Illinois.
Clin Cancer Res ; 23(8): 2019-2026, 2017 04 15.
Article em En | MEDLINE | ID: mdl-27797974
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tamoxifeno / Neoplasias da Mama / Antineoplásicos Hormonais / Citocromo P-450 CYP2D6 Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão País de publicação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tamoxifeno / Neoplasias da Mama / Antineoplásicos Hormonais / Citocromo P-450 CYP2D6 Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão País de publicação: Estados Unidos