Comparison of different caloric substrates on intestinal adaptation in the rat.
Gastroenterology
; 96(6): 1514-20, 1989 Jun.
Article
em En
| MEDLINE
| ID: mdl-2785468
ABSTRACT
We compared the relative efficacy of medium- and long-chain triglycerides and dextrose on intestinal adaptation. Parenterally nourished rats received an isocaloric luminal infusion of one of these three substrates for 1 wk into either the jejunum or the ileum. Intestinal mass (mucosal weight and protein content) as well as the in vivo absorption of 5 mM glucose, valine, and aspartic acid were measured. In the jejunum, long-chain triglycerides were the most trophic, whereas in the ileum, long-chain triglycerides and dextrose were equally effective, but significantly more trophic than medium-chain triglycerides. In general, absorptive function was better maintained by dextrose and medium-chain triglycerides than long-chain triglycerides in the jejunum or by dextrose in the ileum. These data demonstrate that the jejunum and ileum respond differently to caloric substrates. Medium-chain triglycerides do not appear to have a clear superiority to long-chain triglycerides or dextrose in producing intestinal adaptation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Adaptação Fisiológica
/
Carboidratos da Dieta
/
Gorduras na Dieta
/
Íleo
/
Jejuno
Limite:
Animals
Idioma:
En
Revista:
Gastroenterology
Ano de publicação:
1989
Tipo de documento:
Article