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Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine.
Harshbarger, Wayne; Gondi, Sudershan; Ficarro, Scott B; Hunter, John; Udayakumar, Durga; Gurbani, Deepak; Singer, William D; Liu, Yan; Li, Lianbo; Marto, Jarrod A; Westover, Kenneth D.
Afiliação
  • Harshbarger W; From the Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 and.
  • Gondi S; From the Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 and.
  • Ficarro SB; the Department of Cancer Biology and Blais Proteomics Center, Dana-Farber Cancer Institute, Boston, Massachusetts 02115.
  • Hunter J; From the Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 and.
  • Udayakumar D; From the Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 and.
  • Gurbani D; From the Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 and.
  • Singer WD; From the Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 and.
  • Liu Y; From the Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 and.
  • Li L; From the Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 and.
  • Marto JA; the Department of Cancer Biology and Blais Proteomics Center, Dana-Farber Cancer Institute, Boston, Massachusetts 02115.
  • Westover KD; From the Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 and kenneth.westover@utsouthwestern.edu.
J Biol Chem ; 292(1): 112-120, 2017 Jan 06.
Article em En | MEDLINE | ID: mdl-27872191

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Proliferação de Células / Dioxolanos / Glutationa S-Transferase pi / Glutationa Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Proliferação de Células / Dioxolanos / Glutationa S-Transferase pi / Glutationa Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos