Screening Mammalian Cells on a Hydrogel: Functionalized Small Molecule Microarray.
Methods Mol Biol
; 1518: 241-255, 2017.
Article
em En
| MEDLINE
| ID: mdl-27873211
ABSTRACT
Mammalian cell-based microarray technology has gained wide attention, for its plethora of promising applications. The platform is able to provide simultaneous information on multiple parameters for a given target, or even multiple target proteins, in a complex biological system. Here we describe the preparation of mammalian cell-based microarrays using selectively captured of human prostate cancer cells (PC-3). This platform was then used in controlled drug release and measuring the associated drug effects on these cancer cells.
Palavras-chave
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hidrogel de Polietilenoglicol-Dimetacrilato
/
Análise em Microsséries
/
Bibliotecas de Moléculas Pequenas
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Methods Mol Biol
Assunto da revista:
BIOLOGIA MOLECULAR
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Singapura