Prenatal cfDNA screening results indicative of maternal neoplasm: survey of current practice and management needs.
Prenat Diagn
; 37(2): 126-132, 2017 Feb.
Article
em En
| MEDLINE
| ID: mdl-27878832
ABSTRACT
OBJECTIVE:
To determine genetic counselors' current practices and management needs for patients with prenatal cfDNA screening results indicative of maternal neoplasm.METHODS:
A survey was completed by genetic counselors recruited via the National Society of Genetic Counselors (NSGC).RESULTS:
Over 300 genetic counselors were surveyed. Almost all participants (95%) were aware that Noninvasive Prenatal Testing (NIPT) results may suggest maternal neoplasm, and 77% reported they would disclose such results. However, only 29% routinely communicate this possibility to patients in a pre-test setting. Management recommendations made by counselors were highly variable, and over half (51.8%) stated they would feel uncomfortable or very uncomfortable counseling a patient with these results. While less than half (44.3%) believed the current benefits of NIPT's ability to suggest maternal neoplasm outweigh its potential harms, 80.2% recognized it would be beneficial in the future. A vast majority of counselors (91.3%) felt institutional or national guidelines were needed for patient management.CONCLUSION:
A majority of counselors neither felt properly equipped nor comfortable counseling patients with prenatal cfDNA results suggestive of maternal neoplasm. This study demonstrates a need for collaboration amongst clinicians, researchers, and laboratories to publish data regarding NIPT results indicative of maternal neoplasm, and for the creation of management guidelines. © 2016 John Wiley & Sons, Ltd.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações Neoplásicas na Gravidez
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Diagnóstico Pré-Natal
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Padrões de Prática Médica
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DNA de Neoplasias
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Atitude do Pessoal de Saúde
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Aconselhamento Genético
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Necessidades e Demandas de Serviços de Saúde
Tipo de estudo:
Diagnostic_studies
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Guideline
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Prognostic_studies
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Qualitative_research
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Screening_studies
Limite:
Female
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Humans
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Pregnancy
Idioma:
En
Revista:
Prenat Diagn
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Estados Unidos