Metabolic fate and detectability of the new psychoactive substances 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25B-NBOMe) and 2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25C-NBOMe) in human and rat urine by GC-MS, LC-MS<sup>n</sup>, and LC-HR-MS/MS approaches.

Caspar, Achim T; Brandt, Simon D; Stoever, Andreas E; Meyer, Markus R; Maurer, Hans H

Metabolic fate and detectability of the new psychoactive substances 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25B-NBOMe) and 2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25C-NBOMe) in human and rat urine by GC-MS, LC-MSⁿ, and LC-HR-MS/MS approaches.

Caspar, Achim T; Brandt, Simon D; Stoever, Andreas E; Meyer, Markus R; Maurer, Hans H.

Afiliação

Caspar AT; Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Saarland University, D-66421, Homburg, Saar, Germany.
Brandt SD; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, James Parsons Building, Byrom Street, Liverpool, L3 3AF, UK.
Stoever AE; Institute of Legal Medicine, University of Munich, D-80336, Munich, Germany.
Meyer MR; Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Saarland University, D-66421, Homburg, Saar, Germany.
Maurer HH; Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Saarland University, D-66421, Homburg, Saar, Germany. Electronic address: hans.maurer@uks.eu.

J Pharm Biomed Anal ; 134: 158-169, 2017 Feb 05.

Article em En | MEDLINE | ID: mdl-27915193

Assuntos

Anisóis/urina; Benzilaminas/urina; Cromatografia Gasosa-Espectrometria de Massas/métodos; Fenetilaminas/urina; Psicotrópicos/urina; Espectrometria de Massas em Tandem/métodos; Animais; Anisóis/metabolismo; Benzilaminas/metabolismo; Cromatografia Líquida/métodos; Humanos; Insetos; Masculino; Fenetilaminas/metabolismo; Psicotrópicos/metabolismo; Ratos; Ratos Wistar

Palavras-chave

25B-NBOMe; 25C-NBOMe; Cytochrome-P450; LCHRMS/MS; LCMS(n); Metabolism; New psychoactive substance

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenetilaminas / Psicotrópicos / Benzilaminas / Espectrometria de Massas em Tandem / Anisóis / Cromatografia Gasosa-Espectrometria de Massas Limite: Animals / Humans / Male Idioma: En Revista: J Pharm Biomed Anal Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido

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