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Two new phenylpropanoids from Swertia atroviolacea and their anti-5α-reductase activity.
Wu, Hai-Yan; Kan, Xue-Qing; Sheng, Yu; Mou, Lin-Yun; Yang, Qing-Song; Hu, Qiu-Feng; Li, Gan-Peng.
Afiliação
  • Wu HY; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
  • Kan XQ; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
  • Sheng Y; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
  • Mou LY; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
  • Yang QS; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
  • Hu QF; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
  • Li GP; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
Nat Prod Res ; 31(12): 1431-1436, 2017 Jun.
Article em En | MEDLINE | ID: mdl-27917657
ABSTRACT
Two new phenylpropanoids (1-2), together with two known lignans (3-4), were isolated from whole herb of Swertia atroviolacea. The structures of the new metabolites were established on the basis of detailed spectroscopic analysis. Compounds 1 and 2 were evaluated for their anti-5α-reductase activity. The results revealed that 1 and 2 showed weak activity with reductase inhibitions of 45.6 ± 2.8% and 38.4 ± 2.5%, respectively.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenilpropionatos / Swertia / Inibidores de 5-alfa Redutase Idioma: En Revista: Nat Prod Res Ano de publicação: 2017 Tipo de documento: Article País de publicação: ENGLAND / ESCOCIA / GB / GREAT BRITAIN / INGLATERRA / REINO UNIDO / SCOTLAND / UK / UNITED KINGDOM
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenilpropionatos / Swertia / Inibidores de 5-alfa Redutase Idioma: En Revista: Nat Prod Res Ano de publicação: 2017 Tipo de documento: Article País de publicação: ENGLAND / ESCOCIA / GB / GREAT BRITAIN / INGLATERRA / REINO UNIDO / SCOTLAND / UK / UNITED KINGDOM