Novel activities by ebolavirus and marburgvirus interferon antagonists revealed using a standardized in vitro reporter system.

Guito, Jonathan C; Albariño, César G; Chakrabarti, Ayan K; Towner, Jonathan S

Guito, Jonathan C; Albariño, César G; Chakrabarti, Ayan K; Towner, Jonathan S.

Afiliação

Guito JC; Viral Special Pathogens Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Albariño CG; Viral Special Pathogens Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Chakrabarti AK; Viral Special Pathogens Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Towner JS; Viral Special Pathogens Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States. Electronic address: jit8@cdc.gov.

Virology ; 501: 147-165, 2017 01 15.

Article em En | MEDLINE | ID: mdl-27930961

Assuntos

Ebolavirus/metabolismo; Doença pelo Vírus Ebola/virologia; Interferons/antagonistas & inibidores; Doença do Vírus de Marburg/virologia; Marburgvirus/metabolismo; Proteínas Virais/metabolismo; Animais; Ebolavirus/genética; Genes Reporter; Interações Hospedeiro-Patógeno; Humanos; Interferons/metabolismo; Marburgvirus/genética; Proteínas Virais/genética

Palavras-chave

Ebolavirus; Filoviral interferon antagonists; Filoviruses; Innate immune response; Interferon pathway; Marburgvirus; Neglected pathogens; Viral immune evasion; Viral protein function; Virus-host interactions

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais / Interferons / Doença pelo Vírus Ebola / Ebolavirus / Marburgvirus / Doença do Vírus de Marburg Limite: Animals / Humans Idioma: En Revista: Virology Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

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