Effects of pre and post-treatments with dipyridamole in gentamicin-induced acute nephrotoxicity in the rat.

Balakumar, Pitchai; WitnessKoe, Wei Ern; Gan, Yi Syen; JemayPuah, Soo Mei; Kuganesswari, Subramaniam; Prajapati, Sunil Kumar; Varatharajan, Rajavel; Jayachristy, Sam Annie; Sundram, Karupiah; Bahari, Mohd Baidi

Balakumar, Pitchai; WitnessKoe, Wei Ern; Gan, Yi Syen; JemayPuah, Soo Mei; Kuganesswari, Subramaniam; Prajapati, Sunil Kumar; Varatharajan, Rajavel; Jayachristy, Sam Annie; Sundram, Karupiah; Bahari, Mohd Baidi.

Afiliação

Balakumar P; Faculty of Pharmacy, AIMST University, Semeling, 08100 Bedong, Malaysia. Electronic address: pbala2006@gmail.com.
WitnessKoe WE; Faculty of Pharmacy, AIMST University, Semeling, 08100 Bedong, Malaysia.
Gan YS; Faculty of Pharmacy, AIMST University, Semeling, 08100 Bedong, Malaysia.
JemayPuah SM; Faculty of Pharmacy, AIMST University, Semeling, 08100 Bedong, Malaysia.
Kuganesswari S; Faculty of Pharmacy, AIMST University, Semeling, 08100 Bedong, Malaysia.
Prajapati SK; Faculty of Pharmacy, AIMST University, Semeling, 08100 Bedong, Malaysia.
Varatharajan R; Faculty of Pharmacy, AIMST University, Semeling, 08100 Bedong, Malaysia.
Jayachristy SA; Faculty of Medicine, AIMST University, Semeling, 08100 Bedong, Malaysia.
Sundram K; Faculty of Pharmacy, AIMST University, Semeling, 08100 Bedong, Malaysia.
Bahari MB; Faculty of Pharmacy, AIMST University, Semeling, 08100 Bedong, Malaysia.

Regul Toxicol Pharmacol ; 84: 35-44, 2017 Mar.

Article em En | MEDLINE | ID: mdl-27993652

Assuntos

Anti-Inflamatórios/farmacologia; Dipiridamol/farmacologia; Gentamicinas; Necrose Tubular Aguda/tratamento farmacológico; Necrose Tubular Aguda/prevenção & controle; Rim/efeitos dos fármacos; Nefrite/tratamento farmacológico; Nefrite/prevenção & controle; Animais; Biomarcadores/sangue; Creatinina/sangue; Citoproteção; Modelos Animais de Doenças; Interleucina-10/sangue; Rim/metabolismo; Rim/patologia; Necrose Tubular Aguda/sangue; Necrose Tubular Aguda/induzido quimicamente; Masculino; Nefrite/sangue; Nefrite/induzido quimicamente; Ratos Sprague-Dawley; Fatores de Tempo; Ácido Úrico/sangue

Palavras-chave

Acute nephrotoxicity; Dipyridamole; Gentamicin; Renal dysfunction; Renal inflammation; Renoprotection

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Gentamicinas / Dipiridamol / Rim / Necrose Tubular Aguda / Anti-Inflamatórios / Nefrite Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Regul Toxicol Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de publicação: Holanda

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