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Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase.
Koerner, Steffi K; Hanai, Jun-Ichi; Bai, Sha; Jernigan, Finith E; Oki, Miwa; Komaba, Chieko; Shuto, Emi; Sukhatme, Vikas P; Sun, Lijun.
Afiliação
  • Koerner SK; Center for Drug Discovery and Translational Research, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Hanai JI; Divisions of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Nephrology and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Bai S; Center for Drug Discovery and Translational Research, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Jernigan FE; Center for Drug Discovery and Translational Research, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Oki M; Divisions of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Komaba C; Divisions of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Shuto E; Divisions of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Sukhatme VP; Divisions of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Nephrology and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Hematolo
  • Sun L; Center for Drug Discovery and Translational Research, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. Electronic address: lsun1@bidmc.harvard.edu.
Eur J Med Chem ; 126: 920-928, 2017 Jan 27.
Article em En | MEDLINE | ID: mdl-27997879
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: ATP Citrato (pro-S)-Liase / Desenho de Fármacos / Emodina / Inibidores Enzimáticos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: França
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: ATP Citrato (pro-S)-Liase / Desenho de Fármacos / Emodina / Inibidores Enzimáticos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: França