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Downregulation of the ß1 adrenergic receptor in the myocardium results in insensitivity to metoprolol and reduces blood pressure in spontaneously hypertensive rats.
Huang, Yun; Liu, Xiao-Li; Wen, Jia; Huang, Li-Hua; Lu, Yao; Miao, Ru-Jia; Liu, Xing; Li, Ying; Xing, Xiao-Wei; Yuan, Hong.
Afiliação
  • Huang Y; Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, P.R. China.
  • Liu XL; Department of Pharmacy, The Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine, Changsha, Hunan 410013, P.R. China.
  • Wen J; Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, P.R. China.
  • Huang LH; Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, P.R. China.
  • Lu Y; Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, P.R. China.
  • Miao RJ; Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, P.R. China.
  • Liu X; Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, P.R. China.
  • Li Y; Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, P.R. China.
  • Xing XW; Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, P.R. China.
  • Yuan H; Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, P.R. China.
Mol Med Rep ; 15(2): 703-711, 2017 Feb.
Article em En | MEDLINE | ID: mdl-28000860
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pressão Sanguínea / Regulação para Baixo / Receptores Adrenérgicos beta 1 / Metoprolol / Miocárdio / Anti-Hipertensivos Limite: Animals / Humans / Male Idioma: En Revista: Mol Med Rep Ano de publicação: 2017 Tipo de documento: Article País de publicação: Grécia
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pressão Sanguínea / Regulação para Baixo / Receptores Adrenérgicos beta 1 / Metoprolol / Miocárdio / Anti-Hipertensivos Limite: Animals / Humans / Male Idioma: En Revista: Mol Med Rep Ano de publicação: 2017 Tipo de documento: Article País de publicação: Grécia