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Prospective pilot study of CT-guided microwave ablation in the treatment of osteoid osteomas.
Prud'homme, Clara; Nueffer, Jean-Philippe; Runge, Michel; Dubut, Jonathan; Kastler, Bruno; Aubry, Sébastien.
Afiliação
  • Prud'homme C; Department of Musculoskeletal Imaging, University Hospital of Besancon, 25000, Besancon, France.
  • Nueffer JP; Department of Musculoskeletal Imaging, University Hospital of Besancon, 25000, Besancon, France.
  • Runge M; Department of Musculoskeletal Imaging, University Hospital of Besancon, 25000, Besancon, France.
  • Dubut J; Department of Musculoskeletal Imaging, University Hospital of Besancon, 25000, Besancon, France.
  • Kastler B; Department of Musculoskeletal Imaging, University Hospital of Besancon, 25000, Besancon, France.
  • Aubry S; I4S Laboratory, INSERM EA4268, University of Franche-Comte, 25000, Besancon, France.
Skeletal Radiol ; 46(3): 315-323, 2017 Mar.
Article em En | MEDLINE | ID: mdl-28028574
PURPOSE: The aims of this work were to assess the feasibility and efficacy of CT-guided microwave ablation (MWA) in the treatment of osteoid osteomas (OOs). MATERIALS AND METHODS: Thirteen consecutive patients (range 11-31 years old) presenting with OO were prospectively included and treated by CT-guided MWA. Power and duration of MWA were both recorded. The patient's pain was assessed using a numeric pain rating scale (NRS), and side effects were recorded during procedures, after 1 day, 7 days and 1 month. The nidus vascularization and the volume of necrosis induced by MWA were assessed using contrast-enhanced MRI. Success was defined as the complete relief of the patient's pain 1 month after the first procedure, associated with necrosis of the nidus on follow-up MRI. RESULTS: The success rate was up to 92.3% (12/13). At 1 day, 7 days and 1 month, the median NRSs were respectively 5 [interquartile range (IQR) 2-5], 0 (IQR 0-1) and 0 (IQR 0-0). Side effects observed were one partial and self-resolving lesion of a sensory branch of the radial nerve and two skin burns. The median power of the MWA used was 60 W (IQR 50-60) with a 1.5-min duration (IQR 1-2), leading to MWA-induced necrosis measuring on average 23 × 15 × 16 mm. CONCLUSION: CT-guided MWA of OO has a success rate that appears to be almost similar to that of laser or radiofrequency ablation, but care must be taken to prevent nerve or skin lesions.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoma Osteoide / Neoplasias Ósseas / Tomografia Computadorizada por Raios X / Radiografia Intervencionista / Ablação por Cateter / Micro-Ondas Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: Skeletal Radiol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: França País de publicação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoma Osteoide / Neoplasias Ósseas / Tomografia Computadorizada por Raios X / Radiografia Intervencionista / Ablação por Cateter / Micro-Ondas Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: Skeletal Radiol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: França País de publicação: Alemanha