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Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels.
Sennblad, Bengt; Basu, Saonli; Mazur, Johanna; Suchon, Pierre; Martinez-Perez, Angel; van Hylckama Vlieg, Astrid; Truong, Vinh; Li, Yuhuang; Gådin, Jesper R; Tang, Weihong; Grossman, Vera; de Haan, Hugoline G; Handin, Niklas; Silveira, Angela; Souto, Juan Carlos; Franco-Cereceda, Anders; Morange, Pierre-Emmanuel; Gagnon, France; Soria, Jose Manuel; Eriksson, Per; Hamsten, Anders; Maegdefessel, Lars; Rosendaal, Frits R; Wild, Philipp; Folsom, Aaron R; Trégouët, David-Alexandre; Sabater-Lleal, Maria.
Afiliação
  • Sennblad B; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Basu S; Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Sweden.
  • Mazur J; University of Minnesota School of Public Health, Division of Biostatistics, MN, USA.
  • Suchon P; University Medical Center Mainz, Johannes Gutenberg University Mainz, Mainz, Germany.
  • Martinez-Perez A; Institut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1062, Nutrition Obesity and Risk of Thrombosis, Marseille, France; Aix-Marseille University.
  • van Hylckama Vlieg A; Unitat de Genòmica de Malalties Complexes. Institut d'Investigació Biomèdica Sant Pau (IIB-Sant Pau), Barcelona, Spain.
  • Truong V; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
  • Li Y; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
  • Gådin JR; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Tang W; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Grossman V; University of Minnesota School of Public Health, Division of Epidemiology and Community Health, Minneapolis, MN, USA.
  • de Haan HG; University Medical Center Mainz, Johannes Gutenberg University Mainz, Mainz, Germany.
  • Handin N; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
  • Silveira A; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Souto JC; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Franco-Cereceda A; Unitat de Trombosi i Hemostàsia, Hospital de Sant Pau, Barcelona, Spain.
  • Morange PE; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Gagnon F; Institut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1062, Nutrition Obesity and Risk of Thrombosis, Marseille, France; Aix-Marseille University.
  • Soria JM; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
  • Eriksson P; Unitat de Genòmica de Malalties Complexes. Institut d'Investigació Biomèdica Sant Pau (IIB-Sant Pau), Barcelona, Spain.
  • Hamsten A; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Maegdefessel L; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Rosendaal FR; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Wild P; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
  • Folsom AR; University Medical Center Mainz, Johannes Gutenberg University Mainz, Mainz, Germany.
  • Trégouët DA; Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Sabater-Lleal M; DZHK (German Center for Cardiovascular Research), partner site RhineMain, Mainz, Germany.
Hum Mol Genet ; 26(3): 637-649, 2017 02 01.
Article em En | MEDLINE | ID: mdl-28053049
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombose / Moléculas de Adesão Celular / Cininogênios / Receptores de Superfície Celular / Proteínas Adaptadoras de Transdução de Sinal Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia País de publicação: Reino Unido
Texto completo
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Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombose / Moléculas de Adesão Celular / Cininogênios / Receptores de Superfície Celular / Proteínas Adaptadoras de Transdução de Sinal Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia País de publicação: Reino Unido