Prediction of fetal loss by first-trimester crown-rump length in IVF pregnancies.
Arch Gynecol Obstet
; 295(3): 771-775, 2017 Mar.
Article
em En
| MEDLINE
| ID: mdl-28062907
ABSTRACT
OBJECTIVE:
To evaluate the association between small crown-rump length (CRL) and fetal loss ≤22 weeks in IVF pregnancies.METHODS:
A retrospective analysis of prospectively collected data at a university-affiliated medical center. All singleton IVF pregnancies within a 5-year period, with a live embryo on first-trimester ultrasound and verified pregnancy outcome were included. Rates of fetal loss ≤22 weeks were compared between pregnancies with a CRL ≤tenth percentile and above the tenth percentile of our population.RESULTS:
Overall, 397 pregnancies met inclusion criteria. Ninety-five percent of CRL measurements were performed at 40-80 gestational days. All live-embryo's CRL measurements, from 40 to 80 mm, were plotted against expected gestational age (in 5-day clusters), with calculation of the tenth percentile for every gestational age. Total of 64 pregnancies had CRL ≤tenth percentile for gestational age. The rate of fetal loss in this group was significantly higher than in pregnancies with CRL >tenth percentile (17.2 vs. 6.6%, p = 0.005, OR = 2.93, 95% CI 1.2-6.7). In both groups, the majority of fetal losses occurred ≤10 weeks of gestation.CONCLUSION:
In IVF pregnancies with a live embryo, a small CRL at 40-80 days' gestation may predict fetal loss. Repeated ultrasound should be considered after 1-2 weeks.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fertilização in vitro
/
Aborto Espontâneo
/
Estatura Cabeça-Cóccix
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Arch Gynecol Obstet
Assunto da revista:
GINECOLOGIA
/
OBSTETRICIA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Israel