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Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7.
Luo, Yang; de Lange, Katrina M; Jostins, Luke; Moutsianas, Loukas; Randall, Joshua; Kennedy, Nicholas A; Lamb, Christopher A; McCarthy, Shane; Ahmad, Tariq; Edwards, Cathryn; Serra, Eva Goncalves; Hart, Ailsa; Hawkey, Chris; Mansfield, John C; Mowat, Craig; Newman, William G; Nichols, Sam; Pollard, Martin; Satsangi, Jack; Simmons, Alison; Tremelling, Mark; Uhlig, Holm; Wilson, David C; Lee, James C; Prescott, Natalie J; Lees, Charlie W; Mathew, Christopher G; Parkes, Miles; Barrett, Jeffrey C; Anderson, Carl A.
Afiliação
  • Luo Y; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • de Lange KM; Division of Genetics and Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Jostins L; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Moutsianas L; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Randall J; Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, UK.
  • Kennedy NA; Christ Church, University of Oxford, St Aldates, UK.
  • Lamb CA; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • McCarthy S; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Ahmad T; Precision Medicine Exeter, University of Exeter, Exeter, UK.
  • Edwards C; IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK.
  • Serra EG; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne.
  • Hart A; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Hawkey C; Precision Medicine Exeter, University of Exeter, Exeter, UK.
  • Mansfield JC; IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK.
  • Mowat C; Department of Gastroenterology, Torbay Hospital, Torbay, Devon, UK.
  • Newman WG; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Nichols S; Department of Medicine, St Mark's Hospital, Harrow, Middlesex, UK.
  • Pollard M; Nottingham Digestive Diseases Centre, Queens Medical Centre, Nottingham, UK.
  • Satsangi J; Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, UK.
  • Simmons A; Department of Medicine, Ninewells Hospital and Medical School, Dundee, UK.
  • Tremelling M; Genetic Medicine, Manchester Academic Health Science Centre, Manchester, UK.
  • Uhlig H; The Manchester Centre for Genomic Medicine, University of Manchester, Manchester, UK.
  • Wilson DC; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Lee JC; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Prescott NJ; Gastrointestinal Unit, Wester General Hospital University of Edinburgh, Edinburgh, UK.
  • Lees CW; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.
  • Mathew CG; Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
  • Parkes M; Gastroenterology & General Medicine, Norfolk and Norwich University Hospital, Norwich, UK.
  • Barrett JC; Translational Gastroenterology Unit and the Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
  • Anderson CA; Paediatric Gastroenterology and Nutrition, Royal Hospital for Sick Children, Edinburgh, UK.
Nat Genet ; 49(2): 186-192, 2017 Feb.
Article em En | MEDLINE | ID: mdl-28067910

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Adenilil Ciclases / Predisposição Genética para Doença Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Adenilil Ciclases / Predisposição Genética para Doença Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos